Mono- and polysubstance dependent subjects differ on social factors, childhood trauma, personality, suicidal behaviour, and comorbid Axis I diagnoses

Luigi Janiri, Giovanni Martinotti, Vladimir Carli, Daniela Tedeschi, Marco Sarchiapone, V. Carli, M. Di Giannantonio, A. Roy, M. Sarchiapone

Risultato della ricerca: Contributo in rivistaArticolo in rivista

79 Citazioni (Scopus)

Abstract

BACKGROUND: The study aimed to examine the clinical correlates of polysubstance dependence. SUBJECTS AND METHODS: Seven hundred and fifty two substance-dependent subjects were interviewed with the Mini-International Neuropsychiatric Interview, the Brown-Goodwin Assessment for Lifetime History of Aggression (BGLHA), and the Hamilton Depression Rating Scale (HDRS). Subjects completed the Childhood Trauma Questionnaire (CTQ), Eysenck Personality Questionnaire (EPQ), and Barratt Impulsivity Scale (BIS). Subjects found to have polysubstance dependence were compared with subjects with monosubstance dependence. RESULTS: Polysubstance dependence was found in 48.3% of the subjects. Subjects with polysubstance dependence were significantly younger, more were separated/divorced and unemployed, and they had significantly higher CTQ scores for childhood emotional and physical neglect, higher EPQ psychoticism scores, higher BGLHA aggression scores, and higher BIS impulsivity scores. Significantly more of the polysubstance dependent subjects had attempted suicide, self-mutilated, and exhibited aggressive behavior. Significantly more monosubstance dependent subjects had an Axis I psychiatric disorder and they had higher HDRS depression scores. CONCLUSIONS: Polysubstance dependence is common among the groups studied and may be associated with certain socio-demographic, developmental, and personality factors.
Lingua originaleEnglish
pagine (da-a)790-793
Numero di pagine4
RivistaAddictive Behaviors
Volume34
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • Childhood trauma
  • Comorbidity
  • Personality
  • Polysubstance dependence
  • Suicidal behaviour

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