Molecular insights into muscle homeostasis, atrophy and wasting

Bianca Maria Scicchitano, Gabriella Dobrowolny, Gigliola Sica, Antonio Musarò

Risultato della ricerca: Contributo in rivistaArticolo in rivista

19 Citazioni (Scopus)


Muscle homeostasis is guaranteed by a delicate balance between synthesis and degradation of cell proteins and its alteration leads to muscle wasting and diseases. In this review, we describe the major anabolic pathways that are involved in muscle growth and homeostasis and the proteolytic systems that are over-activated in muscle pathologies. Modulation of these pathways comprises an attractive target for drug intervention.
Lingua originaleEnglish
pagine (da-a)356-369
Numero di pagine14
RivistaCurrent Genomics
Stato di pubblicazionePubblicato - 2018


  • Anabolic pathways
  • Degradation of cell proteins
  • Genetics
  • Genetics (clinical)
  • Muscle atrophy
  • Muscle homeostasis
  • Muscle pathologies
  • Muscle wasting


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