Molecular epidemiology of Mycobacterium tuberculosis strains isolated from different regions of Italy and Pakistan

Giovanni Delogu, Giovanni Fadda, La Sechi, S Zanetti, B Montinaro, A Sanna

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

24 Citazioni (Scopus)

Abstract

The use of the (GTG)5 oligonucleotide, a repetitive marker in the Mycobacterium tuberculosis chromosome, as a primer in association with an IS6110 outlooking primer has been successfully applied to a PCR-based fingerprinting method. This method classified 62 strains of M. tuberculosis, isolated from human immunodeficiency virus-seropositive and -seronegative patients in different regions of Italy and Pakistan, as having 53 different patterns. The results were compared with traditional IS6110 fingerprinting, by which 47 distinct patterns were observed.
Lingua originaleEnglish
pagine (da-a)1825-1828
Numero di pagine4
RivistaJournal of Clinical Microbiology
Volume34
Stato di pubblicazionePubblicato - 1996

Keywords

  • AIDS-Related Opportunistic Infections
  • Bacterial Typing Techniques
  • Base Sequence
  • DNA Fingerprinting
  • DNA Primers
  • DNA Transposable Elements
  • Evaluation Studies as Topic
  • Genetic Markers
  • HIV Seronegativity
  • HIV Seropositivity
  • Humans
  • Italy
  • Molecular Epidemiology
  • Mycobacterium tuberculosis
  • Pakistan
  • Polymerase Chain Reaction
  • Repetitive Sequences, Nucleic Acid
  • Tuberculosis, Pulmonary

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