Molecular characterization of human adenoviruses isolated in Italy

Michela Sali, Silvia Fontana, Elena De Carolis, Paola Cattani Franchi, Stefania Manzara, Giovanni Fadda, Giuseppina La Rosa, Michele Muscillo, Marcello Iaconelli, Antonio Di Grazia, Stefano Fontana

Risultato della ricerca: Contributo in rivistaArticolo in rivista

10 Citazioni (Scopus)

Abstract

There is little information on the epidemiology of Human Adenoviruses (HAdVs) in Italy. In this study, 103 HAdV isolates, collected by the A. Gemelli Hospital (Catholic University Medical School of Rome, Italy) between 1987 and 2005, were genotyped by sequencing and phylogenetic analysis on a partial hexon gene region. Nine different serotypes belonging to all six HAdV species were identified. Serotype 2 was the most frequent (53.4%), followed by serotype 1 (15.53%) and serotype 41 (9.7%). Partial-hexon-based identification was confirmed as an effective tool for studying the molecular epidemiology of HAdVs.
Lingua originaleEnglish
pagine (da-a)177-184
Numero di pagine8
RivistaNew Microbiologica
Volume29
Stato di pubblicazionePubblicato - 2006

Keywords

  • Adenovirus Infections, Human
  • Adenoviruses, Human
  • Capsid Proteins
  • Genotype
  • Humans
  • Italy
  • Phylogeny
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Serotyping

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