Modern Management of Esophageal Cancer: Radio-Oncology in Neoadjuvancy, Adjuvancy and Palliation

Francesco Cellini, Stefania Manfrida, Calogero Casà, Angela Romano, Alessandra Arcelli, Alice Zamagni, Viola De Luca, Giuseppe Ferdinando Colloca, Andrea D’Aviero, Lorenzo Fuccio, Valentina Lancellotta, Luca Tagliaferri, Luca Boldrini, Gian Carlo Mattiucci, Maria Antonietta Gambacorta, Alessio Giuseppe Morganti, Vincenzo Valentini

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

The modern management of esophageal cancer is crucially based on a multidisciplinary and multimodal approach. Radiotherapy is involved in neoadjuvant and adjuvant settings; moreover, it includes radical and palliative treatment intention (with a focus on the use of a stent and its potential integration with radiotherapy). In this review, the above-mentioned settings and approaches will be described. Referring to available international guidelines, the background evidence bases will be reviewed, and the ongoing, more relevant trials will be outlined. Target definitions and radiotherapy doses to administer will be mentioned. Peculiar applications such as brachytherapy (interventional radiation oncology), and data regarding innovative approaches including MRI-guided-RT and radiomic analysis will be reported. A focus on the avoidance of surgery for major clinical responses (particularly for SCC) is detailed.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaCancers
Volume14
DOI
Stato di pubblicazionePubblicato - 2022

Keywords

  • CTV
  • Esophageal cancer
  • Guidelines
  • MR guided RT
  • Ongoing trials
  • Palliation
  • Radiotherapy
  • Review
  • Stent

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