Miliary tuberculosis leading to acute respiratory distress syndrome: Clinical experience in pediatric intensive care

Marco Piastra, Piero Valentini, Giorgio Conti, Massimo Antonelli, Gennaro De Pascale, Enzo Picconi, Tony Christian Morena, Danilo Buonsenso, Andrea M. Wolfler, Giovanna Chidini, Martí Pons-Òdena

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Acute respiratory distress syndrome (ARDS) represents a rare complication of miliary tuberculosis (TB) in the adult setting, and it is even less common in the pediatric population. The presence of comorbidities and the possibility of a delayed diagnosis may further impair the clinical prognosis of critically ill patients with disseminated TB and acute respiratory failure. In this report, we present a case series of five pediatric patients with miliary TB and ARDS, where rescue and multimodal respiratory support strategies have been applied with a favorable outcome in more than half of them. The burden of miliary TB over time on a general pediatric intensive care unit—including two ARDS patients—is also illustrated.
Lingua originaleEnglish
pagine (da-a)2003-2010
Numero di pagine8
RivistaPediatric Pulmonology
Volume54
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • ARDS
  • HFOV
  • Pott disease
  • intratracheal surfactant
  • miliary tuberculosis
  • nebulized DNAase

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