Abstract
Background: The management of Medication overuse headache (MOH) represents a difficult challenge for clinicians and headache experts, particularly for the responder rate after a successful withdrawal treatment. The purpose of this study was to investigate the role of demographic and clinical characteristics as well as the score of Migraine-Specific Quality of Life Questionnaire (MSQ), Migraine Disability Questionnaire and Leeds Dependence Questionnaire in predicting a response after a successful withdrawal treatment in patients with MOH. Methods: This ancillary study is part of a randomized trial that demonstrated the safety and the efficacy of a 3-month treatment with sodium valproate (VPA) (800 mg/day vs placebo) in MOH. Demographic and clinical characteristics and questionnaire results were obtained from the entire sample. Results: A significant correlation was found only between MOH relapse and the total MSQ score, the Role Preventive sub-scale and the Emotional Function sub-scale, suggesting a poorer quality of life in non responders. Conclusion: A high MSQ score could be associated with a poor short-term outcome in MOH patients after a successful treatment with detoxification followed by a new treatment.
Lingua originale | English |
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pagine (da-a) | 1-5 |
Numero di pagine | 5 |
Rivista | BMC Neurology |
Volume | 15 |
DOI | |
Stato di pubblicazione | Pubblicato - 2015 |
Keywords
- Adult
- Female
- Headache Disorders, Secondary
- Humans
- MOH
- MSQ
- Male
- Middle Aged
- Migraine Disorders
- Multicenter Studies as Topic
- Outcome Assessment, Health Care
- Quality of Life
- Randomized Controlled Trials as Topic
- Recurrence
- Relapse
- Severity of Illness Index
- Surveys and Questionnaires