MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia

  • L De Paoli
  • , Mv Cerri
  • , S Monti
  • , S Rasi
  • , V Spina
  • , A Bruscaggin
  • , M Greco
  • , C Ciardullo
  • , R Famà
  • , S Cresta
  • , R Maffei
  • , M Ladetto
  • , Maurizio Martini
  • , Luca Laurenti
  • , F Forconi
  • , R Marasca
  • , Luigi Maria Larocca
  • , F Bertoni
  • , G Gaidano
  • , D. Rossi

Risultato della ricerca: Contributo in rivistaArticolo

46 Citazioni (Scopus)

Abstract

Although modern treatment strategies are highly eff ective in many cases of progressive chronic lymphocytic leukemia (CLL), a challenging subgroup of patients show poor response to standard regimens and a survival of less than 2 years [1]. In addition, a proportion of CLL ( ∼ 10%) undergoes transformation into diff use large B-cell lymphoma, an almost invariably lethal complication known as Richter syndrome (RS) [2,3].
Lingua originaleInglese
pagine (da-a)N/A-N/A
RivistaLEUKEMIA & LYMPHOMA
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Chronic Lymphocytic Leukemia

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