MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia

Maurizio Martini, Luca Laurenti, Luigi Maria Larocca, L De Paoli, Mv Cerri, S Monti, S Rasi, V Spina, A Bruscaggin, M Greco, C Ciardullo, R Famà, S Cresta, R Maffei, M Ladetto, F Forconi, R Marasca, F Bertoni, G Gaidano, D. Rossi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

44 Citazioni (Scopus)

Abstract

Although modern treatment strategies are highly eff ective in many cases of progressive chronic lymphocytic leukemia (CLL), a challenging subgroup of patients show poor response to standard regimens and a survival of less than 2 years [1]. In addition, a proportion of CLL ( ∼ 10%) undergoes transformation into diff use large B-cell lymphoma, an almost invariably lethal complication known as Richter syndrome (RS) [2,3].
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaLEUKEMIA & LYMPHOMA
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Chronic Lymphocytic Leukemia

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