Metformin treatment does not affect total leptin levels and free leptin index in obese patients with polycystic ovary syndrome

Antonio Lanzone, Daniela Romualdi, Giuseppe Campagna, Luigi Selvaggi, Maurizio Guido, R Cento, C Proto

Risultato della ricerca: Contributo in rivistaArticolo in rivista

19 Citazioni (Scopus)

Abstract

Leptin, particularly in its free form, is deeply involved in the regulation of energy balance. Insulin was suggested to influence plasmatic leptin levels and soluble leptin receptor in humans. However, this study indicates that metformin treatment, although improving insulin levels, does not exert a significant effect on either total leptin level or free leptin index in obese women with hyperinsulinemia and PCOS.
Lingua originaleEnglish
pagine (da-a)1273-1276
Numero di pagine4
RivistaFertility and Sterility
Volume89
DOI
Stato di pubblicazionePubblicato - 2008

Keywords

  • Adult
  • Female
  • Humans
  • Hyperinsulinism
  • Hypoglycemic Agents
  • Insulin
  • Leptin
  • Metformin
  • Obesity
  • Polycystic Ovary Syndrome

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