Metformin improves endothelial function in type 1 diabetic subjects: a pilot, placebo-controlled randomized study

Dario Pitocco, Bianca Rocca, Gaetano Antonio Lanza, Filippo Crea, Francesco Zaccardi, Pierpaolo Tarzia, Maria Milo, Giuseppe Scavone, Paola Rizzo, Francesca Pagliaccia, Roberto Nerla, Antonino Di Franco, Giovanni Ghirlanda

Risultato della ricerca: Contributo in rivistaArticolo in rivista

44 Citazioni (Scopus)

Abstract

Several studies have investigated the effects of metformin treatment in patients with type 1 diabetes mellitus (T1DM). No study has hitherto examined its effects on endothelial function in these patients. In this study we sought to evaluate the effect of metformin on endothelial function in type 1 diabetic patients.
Lingua originaleEnglish
pagine (da-a)427-431
Numero di pagine5
RivistaDiabetes, obesity & metabolism
Volume15
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • Adult
  • Biological Markers
  • Blood Glucose
  • Brachial Artery
  • Diabetes Mellitus, Type 1
  • Dinoprost
  • Double-Blind Method
  • Drug Therapy, Combination
  • Endothelium, Vascular
  • Female
  • Hemoglobin A, Glycosylated
  • Humans
  • Hypoglycemic Agents
  • Insulin
  • Male
  • Metformin
  • Oxidative Stress
  • Pilot Projects
  • Treatment Outcome
  • Vasodilation

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