TY - JOUR
T1 - Meningeal hemangiopericytoma only diagnosed at the time of late bone metastasis
AU - Satayasoontorn, K
AU - Righi, A
AU - Gambarotti, M
AU - Merlino, Biagio
AU - Brunocilla, E
AU - Vanel, D.
PY - 2014
Y1 - 2014
N2 - Hemangiopericytoma is a rare neoplasm. Primary meningeal hemangiopericytomas account for 1 to 7% of all meningeal tumors. In the literature, meningeal hemangiopericytomas are mainly case reports, which confirm an aggressive behavior with a high rate of local recurrence and extracranial metastasis. Metastasis can be seen many years after initial surgical excision of the primary tumor, and the most common sites include the bone, liver and lung. We present a pathological study of four meningeal hemangiopericytomas with bone metastases. All patients are male with a mean age of 46.5 years. Metastases only involved bone. Three out of four lesions were initially misdiagnosed as meningiomas. Only one case was initially correctly diagnosed as meningeal hemangiopericytoma. All patients underwent surgery with complete resection. Only the patient immediately diagnosed with meningeal hemangiopericytoma received postoperative radiation therapy. Three patients had bone metastases without local recurrence including the one who received radiation therapy. One patient recurred locally after 7 years, and bone metastasis was found at the same time. Our cases confirm that meningeal hemangiopericytomas are a separate entity and have a high recurrence rate despite complete surgical resection, with extracranial metastases, mainly to bone, even after long intervals.
AB - Hemangiopericytoma is a rare neoplasm. Primary meningeal hemangiopericytomas account for 1 to 7% of all meningeal tumors. In the literature, meningeal hemangiopericytomas are mainly case reports, which confirm an aggressive behavior with a high rate of local recurrence and extracranial metastasis. Metastasis can be seen many years after initial surgical excision of the primary tumor, and the most common sites include the bone, liver and lung. We present a pathological study of four meningeal hemangiopericytomas with bone metastases. All patients are male with a mean age of 46.5 years. Metastases only involved bone. Three out of four lesions were initially misdiagnosed as meningiomas. Only one case was initially correctly diagnosed as meningeal hemangiopericytoma. All patients underwent surgery with complete resection. Only the patient immediately diagnosed with meningeal hemangiopericytoma received postoperative radiation therapy. Three patients had bone metastases without local recurrence including the one who received radiation therapy. One patient recurred locally after 7 years, and bone metastasis was found at the same time. Our cases confirm that meningeal hemangiopericytomas are a separate entity and have a high recurrence rate despite complete surgical resection, with extracranial metastases, mainly to bone, even after long intervals.
KW - Meningeal hemangiopericytoma
KW - Meningioma
KW - Misdiagnosis
KW - Meningeal hemangiopericytoma
KW - Meningioma
KW - Misdiagnosis
UR - https://publicatt.unicatt.it/handle/10807/63682
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84930365478&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84930365478&origin=inward
U2 - 10.1007/s00256-014-1926-2
DO - 10.1007/s00256-014-1926-2
M3 - Article
SN - 0364-2348
VL - 43
SP - 1543
EP - 1549
JO - Skeletal Radiology
JF - Skeletal Radiology
IS - 11
ER -