Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

Angela Santoro; Giuseppe Angelico; Vincenzo Fiorentino; Qianqian Zhang; Saveria Spadola; Angela Carlino; Alejandro Martin Sanchez; Gianluca Franceschini; Gian Franco Zannoni; Antonino Mule'

doi:10.3390/diagnostics11040709

Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

Angela Santoro
, Giuseppe Angelico
, Vincenzo Fiorentino
, Qianqian Zhang
, Saveria Spadola
, Angela Carlino
, Alejandro Martin Sanchez
, Gianluca Franceschini
, Gian Franco Zannoni
, Antonino Mule'

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral growth factors are considered essential.

Lingua originale	Inglese
pagine (da-a)	709-709
Numero di pagine	9
Rivista	Diagnostics
Volume	11
DOI	https://doi.org/10.3390/diagnostics11040709
Stato di pubblicazione	Pubblicato - 2021

Keywords

breast carcinoma
breast melanosis
melanocyte colonization
melanoma
pigmentation

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10.3390/diagnostics11040709

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title = "Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature",

abstract = "Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral growth factors are considered essential.",

keywords = "breast carcinoma, breast melanosis, melanocyte colonization, melanoma, pigmentation, breast carcinoma, breast melanosis, melanocyte colonization, melanoma, pigmentation",

author = "Angela Santoro and Giuseppe Angelico and Vincenzo Fiorentino and Qianqian Zhang and Saveria Spadola and Angela Carlino and Sanchez, \{Alejandro Martin\} and Gianluca Franceschini and Zannoni, \{Gian Franco\} and Antonino Mule'",

year = "2021",

doi = "10.3390/diagnostics11040709",

language = "English",

volume = "11",

pages = "709--709",

journal = "Diagnostics",

issn = "2075-4418",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

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TY - JOUR

T1 - Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

AU - Santoro, Angela

AU - Angelico, Giuseppe

AU - Fiorentino, Vincenzo

AU - Zhang, Qianqian

AU - Spadola, Saveria

AU - Carlino, Angela

AU - Sanchez, Alejandro Martin

AU - Franceschini, Gianluca

AU - Zannoni, Gian Franco

AU - Mule', Antonino

PY - 2021

Y1 - 2021

N2 - Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral growth factors are considered essential.

AB - Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral growth factors are considered essential.

KW - breast carcinoma

KW - breast melanosis

KW - melanocyte colonization

KW - melanoma

KW - pigmentation

KW - breast carcinoma

KW - breast melanosis

KW - melanocyte colonization

KW - melanoma

KW - pigmentation

UR - http://hdl.handle.net/10807/178081

U2 - 10.3390/diagnostics11040709

DO - 10.3390/diagnostics11040709

M3 - Article

SN - 2075-4418

VL - 11

SP - 709

EP - 709

JO - Diagnostics

JF - Diagnostics

ER -

Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

Abstract

Keywords

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