Mechanisms, prevention and treatment of distal embolization

Italo Porto; Giovanni Luigi De Maria; Maurizio Pieroni; Leonardo Bolognese; Filippo Crea

doi:10.2174/1381612811319250006

Mechanisms, prevention and treatment of distal embolization

Italo Porto, Giovanni Luigi De Maria, Maurizio Pieroni, Leonardo Bolognese, Filippo Crea

IRCCS Policlinico San Donato

Risultato della ricerca: Contributo in rivista › Articolo in rivista

4 Citazioni (Scopus)

Abstract

Distal embolization (DE) can be either spontaneous or iatrogenic, occurring during percutaneous coronary intervention (PCI). The nature, composition and biochemical properties of embolized material differ according to the setting in which DE occurs: acute coronary syndromes (ACS) or stable coronary artery disease (CAD). DE occurrence is related to increased cardiac biomarkers, negative left ventricular remodeling and associated with a poor prognosis. Prevention and treatment of DE represent some of the most debated topics in interventional cardiology. This review paper is focused on mechanisms of DE and on the strategies for its prevention and treatment in both ACS and stable CAD.

Lingua originale	English
pagine (da-a)	4576-4585
Numero di pagine	10
Rivista	Current Pharmaceutical Design
Volume	19
DOI	https://doi.org/10.2174/1381612811319250006
Stato di pubblicazione	Pubblicato - 2013

Keywords

Acute Coronary Syndrome
Coronary Artery Disease
Embolism
Humans
Prognosis

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10.2174/1381612811319250006

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abstract = "Distal embolization (DE) can be either spontaneous or iatrogenic, occurring during percutaneous coronary intervention (PCI). The nature, composition and biochemical properties of embolized material differ according to the setting in which DE occurs: acute coronary syndromes (ACS) or stable coronary artery disease (CAD). DE occurrence is related to increased cardiac biomarkers, negative left ventricular remodeling and associated with a poor prognosis. Prevention and treatment of DE represent some of the most debated topics in interventional cardiology. This review paper is focused on mechanisms of DE and on the strategies for its prevention and treatment in both ACS and stable CAD.",

keywords = "Acute Coronary Syndrome, Coronary Artery Disease, Embolism, Humans, Prognosis, Acute Coronary Syndrome, Coronary Artery Disease, Embolism, Humans, Prognosis",

author = "Italo Porto and {De Maria}, {Giovanni Luigi} and Maurizio Pieroni and Leonardo Bolognese and Filippo Crea",

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T1 - Mechanisms, prevention and treatment of distal embolization

AU - Porto, Italo

AU - De Maria, Giovanni Luigi

AU - Pieroni, Maurizio

AU - Bolognese, Leonardo

AU - Crea, Filippo

PY - 2013

Y1 - 2013

N2 - Distal embolization (DE) can be either spontaneous or iatrogenic, occurring during percutaneous coronary intervention (PCI). The nature, composition and biochemical properties of embolized material differ according to the setting in which DE occurs: acute coronary syndromes (ACS) or stable coronary artery disease (CAD). DE occurrence is related to increased cardiac biomarkers, negative left ventricular remodeling and associated with a poor prognosis. Prevention and treatment of DE represent some of the most debated topics in interventional cardiology. This review paper is focused on mechanisms of DE and on the strategies for its prevention and treatment in both ACS and stable CAD.

AB - Distal embolization (DE) can be either spontaneous or iatrogenic, occurring during percutaneous coronary intervention (PCI). The nature, composition and biochemical properties of embolized material differ according to the setting in which DE occurs: acute coronary syndromes (ACS) or stable coronary artery disease (CAD). DE occurrence is related to increased cardiac biomarkers, negative left ventricular remodeling and associated with a poor prognosis. Prevention and treatment of DE represent some of the most debated topics in interventional cardiology. This review paper is focused on mechanisms of DE and on the strategies for its prevention and treatment in both ACS and stable CAD.

KW - Acute Coronary Syndrome

KW - Coronary Artery Disease

KW - Embolism

KW - Humans

KW - Prognosis

KW - Acute Coronary Syndrome

KW - Coronary Artery Disease

KW - Embolism

KW - Humans

KW - Prognosis

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DO - 10.2174/1381612811319250006

M3 - Article

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VL - 19

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EP - 4585

JO - Current Pharmaceutical Design

JF - Current Pharmaceutical Design

ER -

Mechanisms, prevention and treatment of distal embolization

Abstract

Keywords

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