Mechanisms involved in cardioprotective effects of pravastatin administered during reoxygenation in human myocardium in vitro

Sandrine Lemoine; Stéphane Allouche; Laurent Coulbault; Valérie Cornet; Massimo Massetti; Philippe Galera; Jean-Louis Gérard; Jean-Luc Hanouz

doi:10.1097/ALN.0b013e31824be77c

Mechanisms involved in cardioprotective effects of pravastatin administered during reoxygenation in human myocardium in vitro

Sandrine Lemoine
, Stéphane Allouche
, Laurent Coulbault
, Valérie Cornet
, Massimo Massetti
, Philippe Galera
, Jean-Louis Gérard
, Jean-Luc Hanouz

Laboratory of Experimental Anesthesiology and Cellular Physiology EA3212
Université de Caen
EA4655 (Team Antibioresistance)

Risultato della ricerca: Contributo in rivista › Articolo

8 Citazioni (Scopus)

Abstract

The authors investigated the effect of pravastatin during reoxygenation after myocardial hypoxia and examined the involvement of nitric oxide synthase, mitochondrial permeability transition pore, and expression of markers of apoptosis in human myocardium in vitro.

Lingua originale	Inglese
pagine (da-a)	824-833
Numero di pagine	10
Rivista	Anesthesiology
Volume	116
DOI	https://doi.org/10.1097/ALN.0b013e31824be77c
Stato di pubblicazione	Pubblicato - 2012

Keywords

Aged
Cardiotonic Agents
Female
Humans
Male
Middle Aged
Myocardium
Organ Culture Techniques
Oxygen Consumption
Pravastatin

Accesso al documento

10.1097/ALN.0b013e31824be77c

Altri file e collegamenti

Link a IRIS PubliCatt

Cita questo

@article{6d241dbddb004c2d9810768fd25fb060,

title = "Mechanisms involved in cardioprotective effects of pravastatin administered during reoxygenation in human myocardium in vitro",

abstract = "The authors investigated the effect of pravastatin during reoxygenation after myocardial hypoxia and examined the involvement of nitric oxide synthase, mitochondrial permeability transition pore, and expression of markers of apoptosis in human myocardium in vitro.",

keywords = "Aged, Cardiotonic Agents, Female, Humans, Male, Middle Aged, Myocardium, Organ Culture Techniques, Oxygen Consumption, Pravastatin, Aged, Cardiotonic Agents, Female, Humans, Male, Middle Aged, Myocardium, Organ Culture Techniques, Oxygen Consumption, Pravastatin",

author = "Sandrine Lemoine and St{\'e}phane Allouche and Laurent Coulbault and Val{\'e}rie Cornet and Massimo Massetti and Philippe Galera and Jean-Louis G{\'e}rard and Jean-Luc Hanouz",

year = "2012",

doi = "10.1097/ALN.0b013e31824be77c",

language = "English",

volume = "116",

pages = "824--833",

journal = "Anesthesiology",

issn = "0003-3022",

publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Mechanisms involved in cardioprotective effects of pravastatin administered during reoxygenation in human myocardium in vitro

AU - Lemoine, Sandrine

AU - Allouche, Stéphane

AU - Coulbault, Laurent

AU - Cornet, Valérie

AU - Massetti, Massimo

AU - Galera, Philippe

AU - Gérard, Jean-Louis

AU - Hanouz, Jean-Luc

PY - 2012

Y1 - 2012

N2 - The authors investigated the effect of pravastatin during reoxygenation after myocardial hypoxia and examined the involvement of nitric oxide synthase, mitochondrial permeability transition pore, and expression of markers of apoptosis in human myocardium in vitro.

AB - The authors investigated the effect of pravastatin during reoxygenation after myocardial hypoxia and examined the involvement of nitric oxide synthase, mitochondrial permeability transition pore, and expression of markers of apoptosis in human myocardium in vitro.

KW - Aged

KW - Cardiotonic Agents

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardium

KW - Organ Culture Techniques

KW - Oxygen Consumption

KW - Pravastatin

KW - Aged

KW - Cardiotonic Agents

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardium

KW - Organ Culture Techniques

KW - Oxygen Consumption

KW - Pravastatin

UR - http://hdl.handle.net/10807/33276

U2 - 10.1097/ALN.0b013e31824be77c

DO - 10.1097/ALN.0b013e31824be77c

M3 - Article

SN - 0003-3022

VL - 116

SP - 824

EP - 833

JO - Anesthesiology

JF - Anesthesiology

ER -

Mechanisms involved in cardioprotective effects of pravastatin administered during reoxygenation in human myocardium in vitro

Abstract

Keywords

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo