Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization

Filippo Crea, Cathleen Noel Bairey Merz, John F Beltrame, Colin Berry, Paolo G Camici, Juan Carlos Kaski, Peter Ong, Carl J Pepine, Udo Sechtem, Hiroaki Shimokawa

Risultato della ricerca: Contributo in rivistaArticolo in rivista

30 Citazioni (Scopus)

Abstract

Persistence or recurrence of angina after a percutaneous coronary intervention (PCI) may affect about 20-40% of patients during short-medium-term follow-up. This appears to be true even when PCI is 'optimized' using physiology-guided approaches and drug-eluting stents. Importantly, persistent or recurrent angina post-PCI is associated with a significant economic burden. Healthcare costs may be almost two-fold higher among patients with persistent or recurrent angina post-PCI vs. those who become symptom-free. However, practice guideline recommendations regarding the management of patients with angina post-PCI are unclear. Gaps in evidence into the mechanisms of post-PCI angina are relevant, and more research seems warranted. The purpose of this document is to review potential mechanisms for the persistence or recurrence of angina post-PCI, propose a practical diagnostic algorithm, and summarize current knowledge gaps.
Lingua originaleEnglish
pagine (da-a)2455-2462
Numero di pagine8
RivistaEuropean Heart Journal
Volume40
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • Coronary microvascular dysfunction
  • Coronary spasm
  • Coronary stenosis
  • Percutaneous coronary intervention
  • Stable angina

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