Abstract
Many experimental evidences point out the correlation between the presence of aluminum-ferritin
complex and neursopathological disorders. In these complexes, two different ranges of Aluminium
(Al) atoms are usually found, i.e., just few atoms or several hundreds. Here, we investigated the invitro
Al-apoferritin binding, with the aim to elucidate the mechanism behind the formation of Alferritin
complexes in-vivo. To this purpose, we studied the mineralization of Al in its ionic and
complexed form with citrate demonstrating that high Al levels found in clinical studies can be
obtained only conveying Al by small physiological ligands.
Lingua originale | English |
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pagine (da-a) | 1-5 |
Numero di pagine | 5 |
Rivista | Applied Physics Letters |
Volume | 2013 |
DOI | |
Stato di pubblicazione | Pubblicato - 2013 |
Keywords
- Aluminium bio-mineralization
- Apoferritin