Measurement of muscle mass in sarcopenia: from imaging to biochemical markers

Matteo Tosato, Emanuele Marzetti, Matteo Cesari, Giulia Savera, Ram R. Miller, Roberto Bernabei, Francesco Landi, Riccardo Calvani

Risultato della ricerca: Contributo in rivistaArticolo in rivista

98 Citazioni (Scopus)


Sarcopenia encompasses the loss of muscle mass and strength/function during aging. Several methods are available for the estimation of muscle or lean body mass. Popular assessment tools include body imaging techniques (e.g., magnetic resonance imaging, computed tomography, dual X-ray absorptiometry, ultrasonography), bioelectric impedance analysis, anthropometric parameters (e.g., calf circumference, mid-arm muscle circumference), and biochemical markers (total or partial body potassium, serum and urinary creatinine, deuterated creatine dilution method). The heterogeneity of the populations to be evaluated as well as the setting in which sarcopenia is investigated impacts the definition of “gold standard” assessment techniques. The aim of this article is to critically review available methods for muscle mass estimation, highlighting strengths and weaknesses of each of them as well as their proposed field of application.
Lingua originaleEnglish
pagine (da-a)19-27
Numero di pagine9
RivistaAging clinical and experimental research
Stato di pubblicazionePubblicato - 2017


  • Appendicular lean mass
  • Biomarkers
  • Body imaging
  • DXA
  • Diagnosis
  • Muscle strength
  • Physical function


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