MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis

Maider Ibarrola-Villava; Hui-Han Hu; Mickaël Guedj; Lara P. Fernandez; Vincent Descamps; Nicole Basset-Seguin; Martine Bagot; Armand Benssussan; Philippe Saiag; Maria Concetta Fargnoli; Ketty Peris; Jose A. Aviles; Ana Lluch; Gloria Ribas; Nadem Soufir

doi:10.1016/j.ejca.2012.03.006

MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis

Maider Ibarrola-Villava
, Hui-Han Hu
, Mickaël Guedj
, Lara P. Fernandez
, Vincent Descamps
, Nicole Basset-Seguin
, Martine Bagot
, Armand Benssussan
, Philippe Saiag
, Maria Concetta Fargnoli
, Ketty Peris
, Jose A. Aviles
, Ana Lluch
, Gloria Ribas
, Nadem Soufir

Risultato della ricerca: Contributo in rivista › Articolo

32 Citazioni (Scopus)

Abstract

Seven genetic biomarkers previously associated with melanoma were analysed in a meta-analysis conducted in three South European populations: five red hair colour (RHC) MC1R alleles, one SLC45A2 variant (p.Phe374Leu) and one thermosensitive TYR variant (p.Arg402Gln). The study included 1639 melanoma patients and 1342 control subjects.

Lingua originale	Inglese
pagine (da-a)	2183-2191
Numero di pagine	9
Rivista	European Journal of Cancer
Volume	48
DOI	https://doi.org/10.1016/j.ejca.2012.03.006
Stato di pubblicazione	Pubblicato - 2012

Keywords

Antigens, Neoplasm
Case-Control Studies
Chi-Square Distribution
Europe
European Continental Ancestry Group
Gene Frequency
Genetic Predisposition to Disease
Hair Color
Humans
Logistic Models
Melanoma
Membrane Transport Proteins
Monophenol Monooxygenase
Multivariate Analysis
Odds Ratio
Phenotype
Polymorphism, Single Nucleotide
Receptor, Melanocortin, Type 1
Risk Assessment
Risk Factors
Skin Neoplasms
Skin Pigmentation

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10.1016/j.ejca.2012.03.006

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Ibarrola-Villava, M., Hu, H.-H., Guedj, M., Fernandez, L. P., Descamps, V., Basset-Seguin, N., Bagot, M., Benssussan, A., Saiag, P., Fargnoli, M. C., Peris, K., Aviles, J. A., Lluch, A., Ribas, G., & Soufir, N. (2012). MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis. European Journal of Cancer, 48, 2183-2191. https://doi.org/10.1016/j.ejca.2012.03.006

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title = "MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis",

abstract = "Seven genetic biomarkers previously associated with melanoma were analysed in a meta-analysis conducted in three South European populations: five red hair colour (RHC) MC1R alleles, one SLC45A2 variant (p.Phe374Leu) and one thermosensitive TYR variant (p.Arg402Gln). The study included 1639 melanoma patients and 1342 control subjects.",

keywords = "Antigens, Neoplasm, Case-Control Studies, Chi-Square Distribution, Europe, European Continental Ancestry Group, Gene Frequency, Genetic Predisposition to Disease, Hair Color, Humans, Logistic Models, Melanoma, Membrane Transport Proteins, Monophenol Monooxygenase, Multivariate Analysis, Odds Ratio, Phenotype, Polymorphism, Single Nucleotide, Receptor, Melanocortin, Type 1, Risk Assessment, Risk Factors, Skin Neoplasms, Skin Pigmentation, Antigens, Neoplasm, Case-Control Studies, Chi-Square Distribution, Europe, European Continental Ancestry Group, Gene Frequency, Genetic Predisposition to Disease, Hair Color, Humans, Logistic Models, Melanoma, Membrane Transport Proteins, Monophenol Monooxygenase, Multivariate Analysis, Odds Ratio, Phenotype, Polymorphism, Single Nucleotide, Receptor, Melanocortin, Type 1, Risk Assessment, Risk Factors, Skin Neoplasms, Skin Pigmentation",

author = "Maider Ibarrola-Villava and Hui-Han Hu and Micka{\"e}l Guedj and Fernandez, \{Lara P.\} and Vincent Descamps and Nicole Basset-Seguin and Martine Bagot and Armand Benssussan and Philippe Saiag and Fargnoli, \{Maria Concetta\} and Ketty Peris and Aviles, \{Jose A.\} and Ana Lluch and Gloria Ribas and Nadem Soufir",

year = "2012",

doi = "10.1016/j.ejca.2012.03.006",

language = "English",

volume = "48",

pages = "2183--2191",

journal = "European Journal of Cancer",

issn = "0959-8049",

publisher = "Elsevier Ltd",

}

Ibarrola-Villava, M, Hu, H-H, Guedj, M, Fernandez, LP, Descamps, V, Basset-Seguin, N, Bagot, M, Benssussan, A, Saiag, P, Fargnoli, MC, Peris, K, Aviles, JA, Lluch, A, Ribas, G & Soufir, N 2012, 'MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis', European Journal of Cancer, vol. 48, pagg. 2183-2191. https://doi.org/10.1016/j.ejca.2012.03.006

TY - JOUR

T1 - MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis

AU - Ibarrola-Villava, Maider

AU - Hu, Hui-Han

AU - Guedj, Mickaël

AU - Fernandez, Lara P.

AU - Descamps, Vincent

AU - Basset-Seguin, Nicole

AU - Bagot, Martine

AU - Benssussan, Armand

AU - Saiag, Philippe

AU - Fargnoli, Maria Concetta

AU - Peris, Ketty

AU - Aviles, Jose A.

AU - Lluch, Ana

AU - Ribas, Gloria

AU - Soufir, Nadem

PY - 2012

Y1 - 2012

N2 - Seven genetic biomarkers previously associated with melanoma were analysed in a meta-analysis conducted in three South European populations: five red hair colour (RHC) MC1R alleles, one SLC45A2 variant (p.Phe374Leu) and one thermosensitive TYR variant (p.Arg402Gln). The study included 1639 melanoma patients and 1342 control subjects.

AB - Seven genetic biomarkers previously associated with melanoma were analysed in a meta-analysis conducted in three South European populations: five red hair colour (RHC) MC1R alleles, one SLC45A2 variant (p.Phe374Leu) and one thermosensitive TYR variant (p.Arg402Gln). The study included 1639 melanoma patients and 1342 control subjects.

KW - Antigens, Neoplasm

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Europe

KW - European Continental Ancestry Group

KW - Gene Frequency

KW - Genetic Predisposition to Disease

KW - Hair Color

KW - Humans

KW - Logistic Models

KW - Melanoma

KW - Membrane Transport Proteins

KW - Monophenol Monooxygenase

KW - Multivariate Analysis

KW - Odds Ratio

KW - Phenotype

KW - Polymorphism, Single Nucleotide

KW - Receptor, Melanocortin, Type 1

KW - Risk Assessment

KW - Risk Factors

KW - Skin Neoplasms

KW - Skin Pigmentation

KW - Antigens, Neoplasm

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Europe

KW - European Continental Ancestry Group

KW - Gene Frequency

KW - Genetic Predisposition to Disease

KW - Hair Color

KW - Humans

KW - Logistic Models

KW - Melanoma

KW - Membrane Transport Proteins

KW - Monophenol Monooxygenase

KW - Multivariate Analysis

KW - Odds Ratio

KW - Phenotype

KW - Polymorphism, Single Nucleotide

KW - Receptor, Melanocortin, Type 1

KW - Risk Assessment

KW - Risk Factors

KW - Skin Neoplasms

KW - Skin Pigmentation

UR - http://hdl.handle.net/10807/56408

U2 - 10.1016/j.ejca.2012.03.006

DO - 10.1016/j.ejca.2012.03.006

M3 - Article

SN - 0959-8049

VL - 48

SP - 2183

EP - 2191

JO - European Journal of Cancer

JF - European Journal of Cancer

ER -

MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis

Abstract

Keywords

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