MANAGEMENT OF PUNDING IN PARKINSON'S DISEASE: AN OPEN-LABEL PROSPECTIVE STUDY

Anna Rita Bentivoglio, Alfonso Fasano, Mauro Pettorruso, Lucia Ricciardi

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39 Citazioni (Scopus)

Abstract

Punding, a peculiar stereotyped behavior characterized by intense fascination with complex, excessive, non-goal-oriented, repetitive activities, is a quite rare condition complicating Parkinson's disease (PD). It is triggered by dopaminergic therapy and could have a strong impact on patient quality of life. No study has specifically investigated medical management of this condition, and only a few anecdotal reports have provided therapeutic hints. Given the suggested similarities to drug-induced dyskinesias, we have previously suggested a multistep algorithm for management of punding. We conducted a prospective open-label study on ten PD punders aimed at testing its validity. In two cases, reduction of levodopa therapy was efficacious; amantadine was effective in controlling punding in four cases; in the remaining cases, quetiapine was employed, with mild efficacy in two cases.
Lingua originaleEnglish
pagine (da-a)656-660
Numero di pagine5
RivistaJournal of Neurology
Volume2011
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Amantadine
  • PARKINSON'S DISEASE
  • Punding
  • Therapy

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