Management of gastrointestinal bleeding in rendu-osler disease

Background: Hereditary hemorrhagic telangiectasia (HHT, or Rendu-Osler-Weber dis-ease) is a rare inherited syndrome, characterized by artero-venous malformations (AVMs or te-langiectasia) with autosomal dominant transmission. AVMs can occur in any organ of the body but most commonly it occurs in the nose, pulmonary, hepatic and cerebral circulations. In patients with HHT, we report teleangectasia of mucosa of the gastrointestinal tract. Methods: Research and online content related to HHT online activity is reviewed, and DOC writ-ing excerpts are used to illustrate key themes. Results: Patients with HHT have a high rate of complications related to bleeding; of them gastrointestinal bleeding accounts for 10.8%. Several therapies, both medical and endoscopic, were utilized to reduce the need for transfusions and hospitalization. Conclusion: A combination of medical and endoscopic therapy is probably the best option.