Management of Esophago-Gastric Junction Carcinoma: A Narrative Multidisciplinary Review

Vincenzo Tondolo, Calogero Casà, Gianluca Rizzo, Mariavittoria Leone, Giuseppe Quero, Virginia Alfieri, Luca Boldrini, Milutin Bulajic, Domenico Cristiano Corsi, Francesco Micciché

Risultato della ricerca: Contributo in rivistaArticolo in rivista


The management of esophagogastric junction (EGJ) cancer is multidisciplinary, and due to its specificity, requires a high-volume center with high medical and surgical expertise. The aim of this narrative review was to critically analyze the evidence and guidelines in the literature and examine the tips and tricks in surgical and medical treatment to increase the long-term outcome of patients with this kind of tumor.Esophagogastric junction (EGJ) carcinoma represents a specific site of disease, given the opportunities for multimodal clinical care and management and the possibilities of combined treatments. It encompasses various clinical subgroups of disease that are heterogeneous and deserve different treatments; therefore, the guidelines have progressively evolved over time, considering the evidence provided by clinical trials. The aim of this narrative review was to summarize the main evidence, which orientates the current guidelines, and to collect the main ongoing studies to address existing gray areas.
Lingua originaleEnglish
pagine (da-a)1-16
Numero di pagine16
Stato di pubblicazionePubblicato - 2023


  • esophago-gastric junction carcinoma
  • mini-invasive surgery
  • multidisciplinary approach
  • preoperative chemoradiotherapy
  • tailored treatment


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