TY - JOUR
T1 - Magnetic resonance imaging appearance of oxidized regenerated cellulose in breast cancer surgery
AU - Giuliani, Michela
AU - Rella, Rossella
AU - Fubelli, Rita
AU - Patrolecco, Federica
AU - Di Giovanni, Silvia Eleonora
AU - Buccheri, Chiara
AU - Padovano, Federico
AU - Belli, Paolo
AU - Romani, Maurizio
AU - Rinaldi, Pierluigi
AU - Bufi, Enida
AU - Franceschini, Gianluca
AU - Bonomo, Lorenzo
PY - 2016
Y1 - 2016
N2 - Purpose: To describe magnetic resonance imaging (MRI) findings in patients who underwent breast-conserving surgery followed by oxidized regenerated cellulose (ORC) implantation in surgical cavity. Materials and methods: We retrospectively reviewed 51 MRI examinations performed between January 2009 and January 2014 in 51 patients who underwent BCS with ORC implantation. Results: In 29/51 (57 %) cases, MRIs showed abnormal findings with three main MRI patterns: (1) complex masses: hyperintense collections on T2-weighted (w) images with internal round hypointense nodules without contrast enhancement (55 %); (2) completely hyperintense collections (17 %); and (3) completely hypointense lesions (28 %). All lesions showed rim enhancement on T1w images obtained in the late phase of the dynamic study with a type 1 curve. Diffusion-weighted imaging was negative in all MRIs and, in particular, 22/29 (76 %) lesions were hyperintense but showing ADC values >1.4 × 10−3mm2/s, while the remaining 7/29 (24 %) lesions were hypointense. In four cases, linear non-mass-like enhancement was detected at the periphery of surgical cavity; these patients were addressed to a short-term follow-up, and the subsequent examinations showed the resolution of these findings. Conclusion: When applied to surgical residual cavity, ORC can lead alterations in surgical scar. This could induce radiologists to misinterpret ultrasonographic and mammographic findings, addressing patients to MRI or biopsy; so knowledge of MRI specific features of ORC, it is essential to avoid misdiagnosis of recurrence.
AB - Purpose: To describe magnetic resonance imaging (MRI) findings in patients who underwent breast-conserving surgery followed by oxidized regenerated cellulose (ORC) implantation in surgical cavity. Materials and methods: We retrospectively reviewed 51 MRI examinations performed between January 2009 and January 2014 in 51 patients who underwent BCS with ORC implantation. Results: In 29/51 (57 %) cases, MRIs showed abnormal findings with three main MRI patterns: (1) complex masses: hyperintense collections on T2-weighted (w) images with internal round hypointense nodules without contrast enhancement (55 %); (2) completely hyperintense collections (17 %); and (3) completely hypointense lesions (28 %). All lesions showed rim enhancement on T1w images obtained in the late phase of the dynamic study with a type 1 curve. Diffusion-weighted imaging was negative in all MRIs and, in particular, 22/29 (76 %) lesions were hyperintense but showing ADC values >1.4 × 10−3mm2/s, while the remaining 7/29 (24 %) lesions were hypointense. In four cases, linear non-mass-like enhancement was detected at the periphery of surgical cavity; these patients were addressed to a short-term follow-up, and the subsequent examinations showed the resolution of these findings. Conclusion: When applied to surgical residual cavity, ORC can lead alterations in surgical scar. This could induce radiologists to misinterpret ultrasonographic and mammographic findings, addressing patients to MRI or biopsy; so knowledge of MRI specific features of ORC, it is essential to avoid misdiagnosis of recurrence.
KW - Absorbable implants
KW - Breast-conserving surgery
KW - Magnetic resonance imaging
KW - Medicine (all)
KW - Oncoplastic procedures
KW - Oxidized regenerated cellulose
KW - Radiology, Nuclear Medicine and Imaging
KW - Absorbable implants
KW - Breast-conserving surgery
KW - Magnetic resonance imaging
KW - Medicine (all)
KW - Oncoplastic procedures
KW - Oxidized regenerated cellulose
KW - Radiology, Nuclear Medicine and Imaging
UR - http://hdl.handle.net/10807/91624
UR - http://link.springer.com/journal/11547
U2 - 10.1007/s11547-016-0656-z
DO - 10.1007/s11547-016-0656-z
M3 - Article
SN - 0033-8362
VL - 121
SP - 688
EP - 695
JO - Radiologia Medica
JF - Radiologia Medica
ER -