Lymphatic Function of the Lower Limb after Groin Dissection for Vulvar Cancer and Reconstruction with Lymphatic SCIP Flap

Anna Amelia Caretto, Gianluigi Stefanizzi, Simona Maria Fragomeni, Alex Federico, Luca Tagliaferri, Valentina Lancellotta, Giovanni Scambia, Stefano Gentileschi

Risultato della ricerca: Contributo in rivistaArticolo in rivista


Inguinofemoral lymphadenectomy, frequently performed for vulvar cancer, is burdened with substantial immediate and long-term morbidity. One of the most disabling treatment-related sequelae is lower limb lymphedema (LLL). The present study aims to describe the wound complications and the severity of LLL in patients who have undergone groin dissection for vulvar cancer and immediate inguinal reconstruction with the Lymphatic Superficial Circumflex Iliac Perforator flap (L-SCIP). We retrospectively reviewed the data of patients who underwent bilateral groin dissection and unilateral inguinal reconstruction with the L-SCIP. The presence and severity of postoperative LLL during the follow-up period were assessed by lymphoscintigraphy and limbs’ volume mea-surement. In addition, immediate complications at the level of the inguinal area were registered. The changes between preoperative and postoperative limb volumes were analyzed by Student’s t test. p values < 0.05 were considered significant. Thirty-one patients were included. The mean variation of volume was 479 ± 330 cc3 in the side where groin reconstruction had been performed, and 683 ± 425 cc3 in the contralateral side, showing smaller variation in the treated side (p = 0.022). Lymphoscintigraphy confirmed the clinical findings. Based on our results, inguinal reconstruction with L-SCIP performed at the same time of groin dissection in patients treated for vulvar cancer can provide a significant protective effect on LLL.
Lingua originaleEnglish
pagine (da-a)1-12
Numero di pagine12
Stato di pubblicazionePubblicato - 2022


  • Groin dissection
  • Gynecologic cancer
  • Inguinal lymphadenectomy
  • Inguinofemoral lymphadenectomy
  • Lymphatic flap
  • Lymphedema
  • Lymphedema prevention
  • Personalized medicine
  • SCIP flap
  • Vulvar cancer


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