TY - JOUR
T1 - Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
AU - Perri, Alessandro
AU - Fattore, Simona
AU - D'Andrea, Vito
AU - Sbordone, Annamaria
AU - Patti, Maria Letizia
AU - Nobile, Stefano
AU - Tirone, Chiara
AU - Giordano, Lucia
AU - Tana, Milena
AU - Priolo, Francesca
AU - Serrao, Francesca
AU - Riccardi, Riccardo
AU - Prontera, Giorgia
AU - Vento, Giovanni
PY - 2022
Y1 - 2022
N2 - Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography score (nLUS) can be used in the diagnostic process, but some authors hypothesise that it is also useful for the management of some neonatal RD. The aim of this study is to analyse the changes in nLUS score before (T0) and after (T1) the start of respiratory support with nasal CPAP in neonates over 32 weeks of age with RD. Thirty-three newborns were enrolled in this retrospective study. LU was performed before and after the start of CPAP. The median nLUS scores at T0 and T1 were 9 (IQR 7–12) and 7 (IQR 4–10), respectively, and showed a significant difference (p < 0.001). The magnitude of reduction in nLUS score, expressed as a percentage, was inversely related to the need for subsequent administration of exogenous surfactant. The study suggests the usefulness of the nLUS score in assessing the response to CPAP in neonates over 32 weeks gestational age.
AB - Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography score (nLUS) can be used in the diagnostic process, but some authors hypothesise that it is also useful for the management of some neonatal RD. The aim of this study is to analyse the changes in nLUS score before (T0) and after (T1) the start of respiratory support with nasal CPAP in neonates over 32 weeks of age with RD. Thirty-three newborns were enrolled in this retrospective study. LU was performed before and after the start of CPAP. The median nLUS scores at T0 and T1 were 9 (IQR 7–12) and 7 (IQR 4–10), respectively, and showed a significant difference (p < 0.001). The magnitude of reduction in nLUS score, expressed as a percentage, was inversely related to the need for subsequent administration of exogenous surfactant. The study suggests the usefulness of the nLUS score in assessing the response to CPAP in neonates over 32 weeks gestational age.
KW - lung ultrasonography
KW - preterm infants
KW - respiratory distress syndrome
KW - lung ultrasonography
KW - preterm infants
KW - respiratory distress syndrome
UR - http://hdl.handle.net/10807/223167
U2 - 10.3390/diagnostics12081909
DO - 10.3390/diagnostics12081909
M3 - Article
SN - 2075-4418
VL - 12
SP - N/A-N/A
JO - Diagnostics
JF - Diagnostics
ER -