Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile

Sr De Rooij; G Nijpels; Pm Nilsson; Jj Nolan; R Gabriel; E Bobbioni Harsch; Geltrude Mingrone; Jm Dekker

doi:10.2337/dc08-1795

Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile

Sr De Rooij, G Nijpels, Pm Nilsson, Jj Nolan, R Gabriel, E Bobbioni Harsch, Geltrude Mingrone, Jm Dekker

Risultato della ricerca: Contributo in rivista › Articolo in rivista

56 Citazioni (Scopus)

Abstract

Low-grade chronic inflammation has been hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by inducing insulin resistance. In the present study, we investigated associations between inflammation markers, insulin sensitivity (expressed as the ratio of the M value to the mean plasma insulin concentrations measured during the final 40 min of the clamp [M/I]), and a range of cardiometabolic risk factors in a large, healthy population.

Lingua originale	English
pagine (da-a)	1295-1301
Numero di pagine	7
Rivista	Diabetes Care
Volume	32
DOI	https://doi.org/10.2337/dc08-1795
Stato di pubblicazione	Pubblicato - 2009

Keywords

Adult
Alcohol Drinking
Cardiovascular Diseases
Cohort Studies
Europe
Female
Heart Diseases
Humans
Inflammation
Insulin Resistance
Leukocyte Count
Life Style
Male
Metabolic Diseases
Middle Aged
Regression Analysis
Risk Factors
Smoking

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De Rooij, S., Nijpels, G., Nilsson, P., Nolan, J., Gabriel, R., Bobbioni Harsch, E., Mingrone, G., & Dekker, J. (2009). Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile. Diabetes Care, 32, 1295-1301. https://doi.org/10.2337/dc08-1795

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abstract = "Low-grade chronic inflammation has been hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by inducing insulin resistance. In the present study, we investigated associations between inflammation markers, insulin sensitivity (expressed as the ratio of the M value to the mean plasma insulin concentrations measured during the final 40 min of the clamp [M/I]), and a range of cardiometabolic risk factors in a large, healthy population.",

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author = "{De Rooij}, Sr and G Nijpels and Pm Nilsson and Jj Nolan and R Gabriel and {Bobbioni Harsch}, E and Geltrude Mingrone and Jm Dekker",

year = "2009",

doi = "10.2337/dc08-1795",

language = "English",

volume = "32",

pages = "1295--1301",

journal = "Diabetes Care",

issn = "1935-5548",

publisher = "American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995",

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De Rooij, S, Nijpels, G, Nilsson, P, Nolan, J, Gabriel, R, Bobbioni Harsch, E, Mingrone, G & Dekker, J 2009, 'Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile', Diabetes Care, vol. 32, pagg. 1295-1301. https://doi.org/10.2337/dc08-1795

TY - JOUR

T1 - Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile

AU - De Rooij, Sr

AU - Nijpels, G

AU - Nilsson, Pm

AU - Nolan, Jj

AU - Gabriel, R

AU - Bobbioni Harsch, E

AU - Mingrone, Geltrude

AU - Dekker, Jm

PY - 2009

Y1 - 2009

N2 - Low-grade chronic inflammation has been hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by inducing insulin resistance. In the present study, we investigated associations between inflammation markers, insulin sensitivity (expressed as the ratio of the M value to the mean plasma insulin concentrations measured during the final 40 min of the clamp [M/I]), and a range of cardiometabolic risk factors in a large, healthy population.

AB - Low-grade chronic inflammation has been hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by inducing insulin resistance. In the present study, we investigated associations between inflammation markers, insulin sensitivity (expressed as the ratio of the M value to the mean plasma insulin concentrations measured during the final 40 min of the clamp [M/I]), and a range of cardiometabolic risk factors in a large, healthy population.

KW - Adult

KW - Alcohol Drinking

KW - Cardiovascular Diseases

KW - Cohort Studies

KW - Europe

KW - Female

KW - Heart Diseases

KW - Humans

KW - Inflammation

KW - Insulin Resistance

KW - Leukocyte Count

KW - Life Style

KW - Male

KW - Metabolic Diseases

KW - Middle Aged

KW - Regression Analysis

KW - Risk Factors

KW - Smoking

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KW - Alcohol Drinking

KW - Cardiovascular Diseases

KW - Cohort Studies

KW - Europe

KW - Female

KW - Heart Diseases

KW - Humans

KW - Inflammation

KW - Insulin Resistance

KW - Leukocyte Count

KW - Life Style

KW - Male

KW - Metabolic Diseases

KW - Middle Aged

KW - Regression Analysis

KW - Risk Factors

KW - Smoking

UR - http://hdl.handle.net/10807/6286

U2 - 10.2337/dc08-1795

DO - 10.2337/dc08-1795

M3 - Article

SN - 1935-5548

VL - 32

SP - 1295

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JO - Diabetes Care

JF - Diabetes Care

ER -

Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile

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Keywords

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