Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

Giovanna Mantini; Valeria Valentini; Bruno Meduri; Stefano Margaritora; Marinella Balducci; F Micciché; Luigia Nardone; Fiorenza De Rose; Alfredo Cesario; Ar Larici; F Maggi; Maria Lucia Calcagni; Pierluigi Granone

doi:10.1016/j.radonc.2012.09.006

Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

Giovanna Mantini, Valeria Valentini, Bruno Meduri, Stefano Margaritora, Marinella Balducci, F Micciché, Luigia Nardone, Fiorenza De Rose, Alfredo Cesario, Ar Larici, F Maggi, Maria Lucia Calcagni, Pierluigi Granone

Risultato della ricerca: Contributo in rivista › Articolo in rivista

13 Citazioni (Scopus)

Abstract

Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).

Lingua originale	English
pagine (da-a)	161-166
Numero di pagine	6
Rivista	Radiotherapy and Oncology
Volume	105
DOI	https://doi.org/10.1016/j.radonc.2012.09.006
Stato di pubblicazione	Pubblicato - 2012

Keywords

nsclc

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

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10.1016/j.radonc.2012.09.006

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Mantini, G., Valentini, V., Meduri, B., Margaritora, S., Balducci, M., Micciché, F., Nardone, L., De Rose, F., Cesario, A., Larici, A., Maggi, F., Calcagni, M. L., & Granone, P. (2012). Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study. Radiotherapy and Oncology, 105, 161-166. https://doi.org/10.1016/j.radonc.2012.09.006

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abstract = "Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).",

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author = "Giovanna Mantini and Valeria Valentini and Bruno Meduri and Stefano Margaritora and Marinella Balducci and F Miccich{\'e} and Luigia Nardone and {De Rose}, Fiorenza and Alfredo Cesario and Ar Larici and F Maggi and Calcagni, {Maria Lucia} and Pierluigi Granone",

year = "2012",

doi = "10.1016/j.radonc.2012.09.006",

language = "English",

volume = "105",

pages = "161--166",

journal = "Radiotherapy and Oncology",

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publisher = "Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114",

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Mantini, G, Valentini, V, Meduri, B, Margaritora, S, Balducci, M, Micciché, F, Nardone, L, De Rose, F, Cesario, A, Larici, A, Maggi, F, Calcagni, ML & Granone, P 2012, 'Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study', Radiotherapy and Oncology, vol. 105, pagg. 161-166. https://doi.org/10.1016/j.radonc.2012.09.006

TY - JOUR

T1 - Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

AU - Mantini, Giovanna

AU - Valentini, Valeria

AU - Meduri, Bruno

AU - Margaritora, Stefano

AU - Balducci, Marinella

AU - Micciché, F

AU - Nardone, Luigia

AU - De Rose, Fiorenza

AU - Cesario, Alfredo

AU - Larici, Ar

AU - Maggi, F

AU - Calcagni, Maria Lucia

AU - Granone, Pierluigi

PY - 2012

Y1 - 2012

N2 - Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).

AB - Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).

KW - nsclc

UR - http://hdl.handle.net/10807/39779

U2 - 10.1016/j.radonc.2012.09.006

DO - 10.1016/j.radonc.2012.09.006

M3 - Article

SN - 0167-8140

VL - 105

SP - 161

EP - 166

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

ER -

Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

Abstract

Keywords

OSS delle Nazioni Unite

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