Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

Giovanna Mantini; Valeria Valentini; Bruno Meduri; Stefano Margaritora; Mario Balducci; Francesco Micciché; Luigia Nardone; Fiorenza De Rose; Alfredo Cesario; Anna Rita Larici; Fabio Maggi; Maria Lucia Calcagni; Pierluigi Granone

doi:10.1016/j.radonc.2012.09.006

Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

Giovanna Mantini, Valeria Valentini, Bruno Meduri, Stefano Margaritora, Mario Balducci, Francesco Micciché, Luigia Nardone, Fiorenza De Rose, Alfredo Cesario, Anna Rita Larici, Fabio Maggi, Maria Lucia Calcagni, Pierluigi Granone

Risultato della ricerca: Contributo in rivista › Articolo in rivista

13 Citazioni (Scopus)

Abstract

Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).

Lingua originale	English
pagine (da-a)	161-166
Numero di pagine	6
Rivista	Radiotherapy and Oncology
Volume	105
DOI	https://doi.org/10.1016/j.radonc.2012.09.006
Stato di pubblicazione	Pubblicato - 2012

Keywords

nsclc

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

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10.1016/j.radonc.2012.09.006

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Mantini, G., Valentini, V., Meduri, B., Margaritora, S., Balducci, M., Micciché, F., Nardone, L., De Rose, F., Cesario, A., Larici, A. R., Maggi, F., Calcagni, M. L., & Granone, P. (2012). Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study. Radiotherapy and Oncology, 105, 161-166. https://doi.org/10.1016/j.radonc.2012.09.006

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title = "Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study",

abstract = "Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).",

keywords = "nsclc, nsclc",

author = "Giovanna Mantini and Valeria Valentini and Bruno Meduri and Stefano Margaritora and Mario Balducci and Francesco Miccich{\'e} and Luigia Nardone and {De Rose}, Fiorenza and Alfredo Cesario and Larici, {Anna Rita} and Fabio Maggi and Calcagni, {Maria Lucia} and Pierluigi Granone",

year = "2012",

doi = "10.1016/j.radonc.2012.09.006",

language = "English",

volume = "105",

pages = "161--166",

journal = "Radiotherapy and Oncology",

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Mantini, G, Valentini, V, Meduri, B, Margaritora, S, Balducci, M, Micciché, F, Nardone, L, De Rose, F, Cesario, A, Larici, AR, Maggi, F, Calcagni, ML & Granone, P 2012, 'Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study', Radiotherapy and Oncology, vol. 105, pagg. 161-166. https://doi.org/10.1016/j.radonc.2012.09.006

TY - JOUR

T1 - Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

AU - Mantini, Giovanna

AU - Valentini, Valeria

AU - Meduri, Bruno

AU - Margaritora, Stefano

AU - Balducci, Mario

AU - Micciché, Francesco

AU - Nardone, Luigia

AU - De Rose, Fiorenza

AU - Cesario, Alfredo

AU - Larici, Anna Rita

AU - Maggi, Fabio

AU - Calcagni, Maria Lucia

AU - Granone, Pierluigi

PY - 2012

Y1 - 2012

N2 - Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).

AB - Low-dose radiotherapy (LDR) (<50 cGy) induces enhanced cell killing in vitro via the hyper-radiation sensitivity phenomenon. Aim of this study was to evaluate the safety and efficacy of a palliative regimen combining pemetrexed and LDR (as a chemopotentiator) on patients affected by recurrent non-small-cell lung cancer (NSCLC).

KW - nsclc

UR - http://hdl.handle.net/10807/39779

U2 - 10.1016/j.radonc.2012.09.006

DO - 10.1016/j.radonc.2012.09.006

M3 - Article

SN - 0167-8140

VL - 105

SP - 161

EP - 166

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

ER -

Low-dose radiotherapy as a chemo-potentiator of a chemotherapy regimen with pemetrexed for recurrent non-small-cell lung cancer: a prospective phase II study

Abstract

Keywords

OSS delle Nazioni Unite

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