Long-term vitreous replacement with perfluorohexyloctane and silicone oil: Preliminary reports of a multicentric study

Stanislao Rizzo, Federica Genovesi-Ebert, Claudia Belting, Flavio Foltran, Enrico Gandolfo, Guido Lesnoni, Ermanno Dell'Omo, Stefano Zenoni, Marco Azzolini, Vito De Molfetta

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Aim: To report on the use of a combined intra-ocular tamponade with silicone oil and perfluorohexyloctane (F6H8) in the treatment of complex retinal detachment. Design: A prospective consecutive interventional case series from seven study centres. Participants: 69 patients presenting a retinal detachment with proliferative vitreoretinopathy (PVR) and retinal breaks of the inferior two quadrants of the fundus. Method: Patients were divided into two groups: (1) 28 eyes which had not been operated on before; (2) 41 eyes affected by recurrent retinal detachment that had had unsuccessful previous surgery with silicone oil or gas tamponade. A pars plana vitrectomy, membrane peeling and - when necessary - a retinotomy were performed; the vitreous cavity was filled with two thirds of F6H8 and one third of silicone oil 1,000 mPas (double filling, DF). The endotamponade was removed after 30-45 days (median 38) and replaced by balanced salt solution or silicone oil according to the condition of the retina. Results: Retinal reattachment was achieved in 52 out of 69 cases (75%) 6 months after removal of the DF without any endotamponade. Conclusion: The DF with F6H 8 and silicone oil allows a good endotamponading to the inferior retina and the posterior pole. The DF appeared to be well tolerated. Further studies are necessary to evaluate whether a DF is advantageous in respect to silicone oil filling alone in case of retinal breaks and PVR of the inferior retina. Copyright © 2005 S. Karger AG.
Lingua originaleEnglish
pagine (da-a)147-153
Numero di pagine7
RivistaOphthalmologica
Volume219
DOI
Stato di pubblicazionePubblicato - 2005

Keywords

  • Long-term vitreous replacement
  • Perfluorohexyloctane (F
  • 6
  • Silicone oil
  • 8
  • )
  • H

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