@article{699ba0ff2f0e45368d0161534b6329b5,
title = "Long-term treatment of somatostatin analog-refractory growth hormone-secreting pituitary tumors with pegvisomant alone or combined with long-acting somatostatin analogs: a retrospective analysis of clinical practice and outcomes",
abstract = "Pegvisomant (PEGV) is widely used, alone or with somatostatin analogs (SSA), for GH-secreting pituitary tumors poorly controlled by SSAs alone. No information is available on specific indications for or relative efficacies of PEGV+SSA versus PEGV monotherapy. Aim of our study was to characterize real-life clinical use of PEGV vs. PEGV+SSA for SSA-resistant acromegaly (patient selection, long-term outcomes, adverse event rates, doses required to achieve control).",
keywords = "Acromegaly, Adolescent, Adult, Aged, Antineoplastic Agents, Hormonal, Female, Growth Hormone-Secreting Pituitary Adenoma, Human Growth Hormone, Humans, Male, Middle Aged, Retrospective Studies, Somatostatin, Treatment Outcome, Young Adult, Acromegaly, Adolescent, Adult, Aged, Antineoplastic Agents, Hormonal, Female, Growth Hormone-Secreting Pituitary Adenoma, Human Growth Hormone, Humans, Male, Middle Aged, Retrospective Studies, Somatostatin, Treatment Outcome, Young Adult",
author = "Antonio Bianchi and Ferdinando Valentini and Raffaella Iuorio and Maurizio Poggi and Roberto Baldelli and Marina Passeri and Antonella Giampietro and Linda Tartaglione and Sabrina Chiloiro and Marialuisa Appetecchia and Patrizia Gargiulo and Andrea Fabbri and Vincenzo Toscano and Alfredo Pontecorvi and {De Marinis Grasso}, Laura",
year = "2013",
doi = "10.1186/1756-9966-32-40",
language = "English",
volume = "32",
pages = "40--40",
journal = "JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH",
issn = "0392-9078",
publisher = "Attuale:APSIT ASSOC PROM STUD IMMUNOL TUMOR, VIALE REGINA ELENA 291, ROME, ITALY, 00161 Centro Ricerca Sperimentale:Via Delle Messi d Oro 156, 00158 Rome Italy:011 39 06 52662536, EMAIL:
[email protected], INTERNET: http://crs.ifo.it, Fax: 011 39 06 52662505",
}