27 Citazioni (Scopus)

Abstract

Infliximab is effective in human and murine IBD, but its pharmacodynamic is still poorly known. The aim of this study was to assess the affinity of infliximab to murine TNF-α, its role in murine colitis when administered intra-rectally and its levels in the blood, gut mucosa and stool of healthy and sick mice.
Lingua originaleEnglish
pagine (da-a)1017-1021
Numero di pagine5
RivistaDIGESTIVE AND LIVER DISEASE
Volume45
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • Faeces
  • Inflammatory bowel disease
  • Infliximab
  • Intestinal mucosa
  • Murine DSS colitis
  • Pharmacokinetic
  • Serum levels

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