Infliximab is effective in human and murine IBD, but its pharmacodynamic is still poorly known. The aim of this study was to assess the affinity of infliximab to murine TNF-α, its role in murine colitis when administered intra-rectally and its levels in the blood, gut mucosa and stool of healthy and sick mice.
Lingua originaleEnglish
pagine (da-a)1017-1021
Numero di pagine5
RivistaDigestive and Liver Disease
Stato di pubblicazionePubblicato - 2013


  • Faeces
  • Inflammatory bowel disease
  • Infliximab
  • Intestinal mucosa
  • Murine DSS colitis
  • Pharmacokinetic
  • Serum levels


Entra nei temi di ricerca di 'Locally injected Infliximab ameliorates murine DSS colitis: differences in serum and intestinal levels of drug between healthy and colitic mice'. Insieme formano una fingerprint unica.

Cita questo