Localization of S-100 protein in Müller cells of the retina--2. Electron microscopical immunocytochemistry

Carlo Gangitano, Fabrizio Michetti, D Cocchia, Jm Polak, G Terenghi, Francesco Battaglia, V Stolfi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

19 Citazioni (Scopus)

Abstract

The cellular and subcellular distribution of S-100 protein was investigated at the ultrastructural level in the rat retina by the immunocytochemical PAP method. S-100 appeared to be localized in the cytoplasm and nucleus of Müller cells, offering conclusive evidence that in the mammalian retina, the protein is confined to glial cells. S-100, as a marker for Müller cells, may be a useful tool in order to study the cytoarchitecture of the retina in normal as well as in pathologic conditions. In addition, the retina may represent a suitable model for further investigation on the biologic role of S-100.
Lingua originaleEnglish
pagine (da-a)980-984
Numero di pagine5
RivistaINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Volume24
Stato di pubblicazionePubblicato - 1983

Keywords

  • Animals
  • Immunologic Techniques
  • Male
  • Microscopy, Electron
  • Nerve Tissue Proteins
  • Neuroglia
  • Rats
  • Rats, Inbred Strains
  • Retina
  • S100 Proteins

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