Abstract
Experience in liver transplantation (OLT) in Italy over a ten-year period is reported. Data were obtained using a multiple-items form collected from Italian liver transplant centres (reference centres) and other Italian institutions actively involved both in the processes of evaluation of the candidates and the follow-up of liver transplant recipients (afference centres). During this period, a total of 1046 liver transplants were performed on 954 patients, with a cumulative proportional survival of 71%. The most common indication for liver transplantation was post-hepatitic cirrhosis due to either hepatitis B virus (+/-hepatitis Delta virus) or hepatitis C virus infection. Good survival rates were observed, particularly in controversial indications, such as alcoholic cirrhosis, post-hepatitic hepatitis B virus-related cirrhosis and hepatocellular carcinoma, most likely due to proper and careful selection of the patients. Cirrhosis, secondary to an autoimmunity-based liver disease, showed the highest rate of rejection episodes. Infections, in our study population, were the most common cause of death after transplantation.
Lingua originale | English |
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pagine (da-a) | 343-350 |
Numero di pagine | 8 |
Rivista | Italian Journal of Gastroenterology |
Volume | 28 |
Stato di pubblicazione | Pubblicato - 1996 |
Keywords
- Adolescent
- Adult
- Female
- Follow-Up Studies
- Graft Rejection
- Graft Survival
- Humans
- Immunosuppressive Agents
- Italy
- Liver Diseases
- Liver Transplantation
- Male
- Postoperative Complications
- Retrospective Studies
- Survival Rate