@article{67ae3d1d3cde4c16a1416a82744ff9d7,
title = "Lithium carbonate in amyotrophic lateral sclerosis: lack of efficacy in a dose-finding trial",
abstract = "A neuroprotective effect of lithium in amyotrophic lateral sclerosis (ALS) has been recently reported. We performed a multicenter trial with lithium carbonate to assess its tolerability, safety, and efficacy in patients with ALS, comparing 2 different target blood levels (0.4-0.8 mEq/L, therapeutic group [TG], vs 0.2-0.4 mEq/L, subtherapeutic group [STG]).",
keywords = "Adolescent, Adult, Aged, Amyotrophic Lateral Sclerosis, Dose-Response Relationship, Drug, Enzyme Inhibitors, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Lithium Carbonate, Male, Middle Aged, Retrospective Studies, Single-Blind Method, Time Factors, Treatment Outcome, Young Adult, Adolescent, Adult, Aged, Amyotrophic Lateral Sclerosis, Dose-Response Relationship, Drug, Enzyme Inhibitors, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Lithium Carbonate, Male, Middle Aged, Retrospective Studies, Single-Blind Method, Time Factors, Treatment Outcome, Young Adult",
author = "A Chi{\`o} and G Borghero and A Calvo and M Capasso and C Caponnetto and M Corbo and F Giannini and G Logroscino and J Mandrioli and N Marcello and L Mazzini and C Moglia and Monsurr{\`o} and G Mora and F Patti and V Pietrini and F Pisano and E Pupillo and Mario Sabatelli and F Salvi and V Silani and Il Simone and G Sorar{\`u} and Tola and P Volanti and E Beghi and M. Perini",
year = "2010",
doi = "10.1212/WNL.0b013e3181ed9e7c",
language = "English",
volume = "75",
pages = "619--625",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320",
}