@article{fbaf43b532ed4edf8647047f5b5ff0f7,
title = "Linezolid plasma and intrapulmonary concentrations in critically ill obese patients with ventilator-associated pneumonia: intermittent vs continuous administration",
abstract = "Clinical application of an antibiotic's pharmacokinetic/pharmacodynamic (PK/PD) properties may improve the outcome of severe infections. No data are available on the use of linezolid (LNZ) continuous infusion in critically ill obese patients affected by ventilator-associated pneumonia (VAP).",
keywords = "Acetamides, Aged, Anti-Bacterial Agents, Critical Illness, Drug Monitoring, Female, Humans, Infusions, Intravenous, Linezolid, Male, Microbial Sensitivity Tests, Middle Aged, Obesity, Organ Dysfunction Scores, Oxazolidinones, Pneumonia, Ventilator-Associated, Prospective Studies, Risk Assessment, Rome, Acetamides, Aged, Anti-Bacterial Agents, Critical Illness, Drug Monitoring, Female, Humans, Infusions, Intravenous, Linezolid, Male, Microbial Sensitivity Tests, Middle Aged, Obesity, Organ Dysfunction Scores, Oxazolidinones, Pneumonia, Ventilator-Associated, Prospective Studies, Risk Assessment, Rome",
author = "{De Pascale}, Gennaro and Serena Fortuna and Mario Tumbarello and Cutuli, {Salvatore Lucio} and Vallecoccia, {Maria Sole} and Teresa Spanu and Giuseppe Bello and Luca Montini and Pennisi, {Mariano Alberto} and Pierluigi Navarra and Massimo Antonelli",
year = "2015",
doi = "10.1007/s00134-014-3550-y",
language = "English",
volume = "41",
pages = "103--110",
journal = "Intensive Care Medicine",
issn = "0342-4642",
publisher = "Berlin; Heidelberg: Springer.",
}