Levosimendan in two neonates with ischemic heart failure and pulmonary hypertension.

Maria Pia De Carolis; Marco Piastra; Iliana Bersani; Manuela Pardeo; Eleonora Stival; A Tempera; Costantino Romagnoli; Giorgio Conti; Gabriella De Rosa

doi:10.1159/000329848

Levosimendan in two neonates with ischemic heart failure and pulmonary hypertension.

Maria Pia De Carolis, Marco Piastra, Iliana Bersani, Manuela Pardeo, Eleonora Stival, A Tempera, Costantino Romagnoli, Giorgio Conti, Gabriella De Rosa

Risultato della ricerca: Contributo in rivista › Articolo

6 Citazioni (Scopus)

Abstract

We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.

Lingua originale	Inglese
pagine (da-a)	201-205
Numero di pagine	5
Rivista	Neonatology
Volume	101
Numero di pubblicazione	3
DOI	https://doi.org/10.1159/000329848
Stato di pubblicazione	Pubblicato - 2012

All Science Journal Classification (ASJC) codes

Pediatria, Perinatologia e Salute del Bambino
Biologia dello Sviluppo

Keywords

Heart failure
Levosimendan
Pulmonary hypertension

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10.1159/000329848

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abstract = "We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.",

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AU - De Carolis, Maria Pia

AU - Piastra, Marco

AU - Bersani, Iliana

AU - Pardeo, Manuela

AU - Stival, Eleonora

AU - Tempera, A

AU - Romagnoli, Costantino

AU - Conti, Giorgio

AU - De Rosa, Gabriella

PY - 2012

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N2 - We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.

AB - We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.

KW - Heart failure

KW - Levosimendan

KW - Pulmonary hypertension

KW - Heart failure

KW - Levosimendan

KW - Pulmonary hypertension

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Levosimendan in two neonates with ischemic heart failure and pulmonary hypertension.

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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