Letrozole in the management of advanced ovarian cancer: An old drug as a new targeted therapy

Giovanni Scambia, Anna Fagotti, Raffaella Ergasti, Francesca De Felice

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

At present, there is no standard of care on the use of letrozole in ovarian cancer management. We performed a systematic review of the available literature addressing this issue. Data demonstrated a role for letrozole in ovarian cancer, in both the primary and recurrent setting. Letrozole, which has a favorable toxicity profile, seems to assure a prolonged recurrence-free interval, particularly when used as maintenance treatment, in low grade serous ovarian cancer; in recurrent cases it had also led to prolonged disease control. However, the optimal setting and biologically relevant patient population needs to be defined in larger trials.
Lingua originaleEnglish
pagine (da-a)1058-1064
Numero di pagine7
RivistaInternational Journal of Gynecological Cancer
Volume30
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • medical oncology
  • ovarian cancer

Fingerprint

Entra nei temi di ricerca di 'Letrozole in the management of advanced ovarian cancer: An old drug as a new targeted therapy'. Insieme formano una fingerprint unica.

Cita questo