TY - JOUR
T1 - Isotretinoin-associated pan-enteritis.
AU - Spada, Cristiano
AU - Riccioni, Maria Elena
AU - Familiari, Pietro
AU - Costamagna, Guido
AU - Marchese, Michele
AU - 33183,
AU - FACOLTA', DI MEDICINA E CHIRURGIA "A.GEMELLI"
AU - traslazionale, ROMA - Dipartimento di Medicina e chirurgia
AU - FACOLTA', DI MEDICINA E CHIRURGIA "A.GEMELLI"
AU - FACOLTA', DI MEDICINA E CHIRURGIA "A.GEMELLI"
AU - FACOLTA', DI MEDICINA E CHIRURGIA "A.GEMELLI"
PY - 2008
Y1 - 2008
N2 - A 22-year-old man has been recently admitted to our Department with a 10-day history of melena. Because of nodular acne, the patient had been treated with Isotretinoin, a 13-cis-retinoic acid (20-mg twice daily, for 15 d). Upper gastrointestinal endoscopy revealed edema and hyperemia of the gastric mucosa of the body and antrum. Flexible sigmoidoscopy revealed edema and hyperemia of the mucosa of the rectum and sigmoid colon with numerous erosions. To exclude the possibility of small bowel involvement the patient underwent video capsule endoscopy that showed a diffuse and extensive intestinal inflammation with multiple linear, irregular-shaped jejunal ulcerations, and apthae. Isotretinoin was discontinued and the patient improved with complete resolution of symptoms.
AB - A 22-year-old man has been recently admitted to our Department with a 10-day history of melena. Because of nodular acne, the patient had been treated with Isotretinoin, a 13-cis-retinoic acid (20-mg twice daily, for 15 d). Upper gastrointestinal endoscopy revealed edema and hyperemia of the gastric mucosa of the body and antrum. Flexible sigmoidoscopy revealed edema and hyperemia of the mucosa of the rectum and sigmoid colon with numerous erosions. To exclude the possibility of small bowel involvement the patient underwent video capsule endoscopy that showed a diffuse and extensive intestinal inflammation with multiple linear, irregular-shaped jejunal ulcerations, and apthae. Isotretinoin was discontinued and the patient improved with complete resolution of symptoms.
KW - ENTERITIS
KW - ENTERITIS
UR - http://hdl.handle.net/10807/32739
M3 - Editorial
VL - 2008
SP - 923
EP - 925
JO - Journal of Clinical Gastroenterology
JF - Journal of Clinical Gastroenterology
SN - 0192-0790
ER -