Is there significant improvement in neonatal outcome after treating pPROM mothers with amnio-infusion?

Marco De Santis, Giovanni Vento, Maria Pia De Carolis, Costantino Romagnoli, Alessandro Caruso, F Piersigilli

Risultato della ricerca: Contributo in rivistaArticolo in rivista

17 Citazioni (Scopus)

Abstract

The aim of this study was to determine the effects of amnio-infusion treatment on fetal and neonatal mortality and neonatal pulmonary development in women with singleton pregnancies and premature rupture of the membranes occurring at a gestational age of <26 weeks and who had severe oligohydramnios. The treated group of 45 consenting women received serial amnio-infusion and was compared with the control group of 44 women who underwent waiting treatment. Our study confirmed a higher number of live births in the treated group, especially in cases with a gestational age at rupture (GAR) of <20 weeks. Furthermore, even if GAR is an important factor for predicting pulmonary hypoplasia, amnio-infusion treatment reduces the probability of pulmonary hypoplasia. In fact, over 20 weeks, amnio-infusion treatment significantly reduces the risk of pulmonary hypoplasia even if normal lung development cannot be guaranteed.
Lingua originaleEnglish
pagine (da-a)222-229
Numero di pagine8
RivistaBIOLOGY OF THE NEONATE
Stato di pubblicazionePubblicato - 2004

Keywords

  • Amnioinfusion
  • Pulmonary development
  • pProm

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