TY - JOUR
T1 - Is there any role for the Hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?
AU - De Carolis, Sara
AU - Botta, Angela
AU - Di Pasquo, Elvira
AU - Del Sordo, Gelsomina
AU - Lanzone, Antonio
AU - De Carolis, Maria Pia
PY - 2015
Y1 - 2015
N2 - The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.
AB - The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.
KW - Hydroxychloroquine
KW - obstetrical antiphospholipid syndrome
KW - Hydroxychloroquine
KW - obstetrical antiphospholipid syndrome
UR - http://hdl.handle.net/10807/66897
U2 - 10.1016/j.autrev.2015.04.010
DO - 10.1016/j.autrev.2015.04.010
M3 - Article
SN - 1568-9972
SP - 760
EP - 762
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
ER -