TY - JOUR
T1 - Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?
AU - Inno, Alessandro
AU - Di Salvatore, Mariantonietta
AU - Cenci, Tonia
AU - Martini, Maurizio
AU - Orlandi, Armando
AU - Strippoli, Antonia
AU - Ferrara, Anna Maria
AU - Bagala', Cinzia
AU - Cassano, Alessandra
AU - Larocca, Luigi Maria
AU - Barone, Carlo Antonio
PY - 2011
Y1 - 2011
N2 - The KRAS mutation is not responsible for all cases of resistance to anti-epidermal growth factor receptors (EGFRs) in metastatic colorectal cancer (mCRC), and new predictive and prognostic factors are actively being sought.
AB - The KRAS mutation is not responsible for all cases of resistance to anti-epidermal growth factor receptors (EGFRs) in metastatic colorectal cancer (mCRC), and new predictive and prognostic factors are actively being sought.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Antibodies, Monoclonal
KW - Antineoplastic Agents
KW - Colorectal Neoplasms
KW - DNA, Neoplasm
KW - Drug Resistance, Neoplasm
KW - Female
KW - Gene Expression Regulation, Neoplastic
KW - Humans
KW - Immunoenzyme Techniques
KW - Male
KW - Middle Aged
KW - Mutation
KW - Neoplasm Metastasis
KW - PTEN Phosphohydrolase
KW - Polymerase Chain Reaction
KW - Prognosis
KW - Proto-Oncogene Proteins
KW - Proto-Oncogene Proteins B-raf
KW - Proto-Oncogene Proteins c-met
KW - Receptor, Epidermal Growth Factor
KW - Receptor, IGF Type 1
KW - Retrospective Studies
KW - Survival Rate
KW - Tumor Markers, Biological
KW - ras Proteins
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Antibodies, Monoclonal
KW - Antineoplastic Agents
KW - Colorectal Neoplasms
KW - DNA, Neoplasm
KW - Drug Resistance, Neoplasm
KW - Female
KW - Gene Expression Regulation, Neoplastic
KW - Humans
KW - Immunoenzyme Techniques
KW - Male
KW - Middle Aged
KW - Mutation
KW - Neoplasm Metastasis
KW - PTEN Phosphohydrolase
KW - Polymerase Chain Reaction
KW - Prognosis
KW - Proto-Oncogene Proteins
KW - Proto-Oncogene Proteins B-raf
KW - Proto-Oncogene Proteins c-met
KW - Receptor, Epidermal Growth Factor
KW - Receptor, IGF Type 1
KW - Retrospective Studies
KW - Survival Rate
KW - Tumor Markers, Biological
KW - ras Proteins
UR - http://hdl.handle.net/10807/25735
U2 - 10.1016/j.clcc.2011.03.028
DO - 10.1016/j.clcc.2011.03.028
M3 - Article
SN - 1533-0028
VL - 10
SP - 325
EP - 332
JO - Clinical Colorectal Cancer
JF - Clinical Colorectal Cancer
ER -