TY - JOUR
T1 - Is Health-Related Quality of Life after Radical Cystectomy Using Validated Questionnaires Really Better in Patients with Ileal Orthotopic Neobladder Compared to Ileal Conduit: A Meta-Analysis of Retrospective Comparative Studies
AU - Cerruto, Maria A.
AU - D'Elia, Carolina
AU - Siracusano, Salvatore
AU - Porcaro, Antonio B.
AU - Cacciamani, Giovanni
AU - Marchi, Davide De
AU - Niero, Mauro
AU - Lonardi, Cristina
AU - Iafrate, Massimo
AU - Bassi, Pierfrancesco
AU - Belgrano, Emanuele
AU - Imbimbo, Ciro
AU - Racioppi, Marco
AU - Talamini, Renato
AU - Ciciliato, Stefano
AU - Toffoli, Laura
AU - Rizzo, Michele
AU - Visalli, Francesco
AU - Verze, Paolo
AU - Artibani, Walter
PY - 2017
Y1 - 2017
N2 - Introduction\r\nFrom the most recent systematic revision of the literature, an orthotopic neobladder would seem to show marginally better health related quality of life (HR-QoL) scores compared with an ileal conduit. The aim of this study was to review all relevant published studies about the comparison between ileal orthotopic neobladder (IONB) and ileal conduit using validated HR-QoL questionnaires.\r\n\r\nMaterials and Methods\r\nStudies were identified by searching multiple literature databases. Data were synthesized using meta-analytic methods conformed to the PRISMA statement.\r\n\r\nResults\r\nThe literature search identified 10 papers; pooled effect sizes of combined quality of life outcomes for ileal conduit versus IONB showed a significantly better HR-QoL in patients with IONB (Hedges' g = 0.278; p = 0.000);. The present study has an important limitation due to the type of the analyzed comparative studies, all retrospective and not randomized.\r\n\r\nConclusion\r\nThis meta-analysis of not-randomized, retrospective comparative studies on the impact of ileal conduit versus IONB on HR-QoL showed a significant advantage of IONB subgroups.
AB - Introduction\r\nFrom the most recent systematic revision of the literature, an orthotopic neobladder would seem to show marginally better health related quality of life (HR-QoL) scores compared with an ileal conduit. The aim of this study was to review all relevant published studies about the comparison between ileal orthotopic neobladder (IONB) and ileal conduit using validated HR-QoL questionnaires.\r\n\r\nMaterials and Methods\r\nStudies were identified by searching multiple literature databases. Data were synthesized using meta-analytic methods conformed to the PRISMA statement.\r\n\r\nResults\r\nThe literature search identified 10 papers; pooled effect sizes of combined quality of life outcomes for ileal conduit versus IONB showed a significantly better HR-QoL in patients with IONB (Hedges' g = 0.278; p = 0.000);. The present study has an important limitation due to the type of the analyzed comparative studies, all retrospective and not randomized.\r\n\r\nConclusion\r\nThis meta-analysis of not-randomized, retrospective comparative studies on the impact of ileal conduit versus IONB on HR-QoL showed a significant advantage of IONB subgroups.
KW - Health related quality of life
KW - Ileal conduit
KW - Neobladder
KW - Radical cystectomy
KW - Urinary diversion
KW - Health related quality of life
KW - Ileal conduit
KW - Neobladder
KW - Radical cystectomy
KW - Urinary diversion
UR - https://publicatt.unicatt.it/handle/10807/181326
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85022322958&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85022322958&origin=inward
U2 - 10.1159/000447153
DO - 10.1159/000447153
M3 - Article
SN - 1527-2737
SP - 57
EP - 68
JO - Current Urology Reports
JF - Current Urology Reports
IS - 10
ER -