TY - JOUR
T1 - Is capillary electrophoresis on microchip devices able to genotype uridine diphosphate glucuronosyltransferase 1A1 TATA-box polymorphisms?
AU - Minucci, Angelo
AU - Canu, Giulia
AU - De Bonis, Maria
AU - Delibato, Elisabetta
AU - Capoluongo, Ettore Domenico
PY - 2014
Y1 - 2014
N2 - In this commentary, we focused our attention on capillary electrophoresis. It achieves the efficient separation of molecular species by the application of high voltages to samples in solution. Actually, capillary electrophoresis can be performed on microchip devices, based on an automated and miniaturized electrophoresis system, based on lab-on-a-chip technology. By this technology it is possible to separate nucleic acid fragments (DNA or RNA) with respect to sizing accuracy and sizing resolution. Currently, two automated capillary electrophoresis on microchips devices are available: the Agilent 2100 Bioanalyzer and the Experion Automated Electrophoresis System. In this study, we evaluated if the CE is able to distinguish the three uridine diphosphate glucuronosyltransferase 1A1 TATA-box genotypes.
AB - In this commentary, we focused our attention on capillary electrophoresis. It achieves the efficient separation of molecular species by the application of high voltages to samples in solution. Actually, capillary electrophoresis can be performed on microchip devices, based on an automated and miniaturized electrophoresis system, based on lab-on-a-chip technology. By this technology it is possible to separate nucleic acid fragments (DNA or RNA) with respect to sizing accuracy and sizing resolution. Currently, two automated capillary electrophoresis on microchips devices are available: the Agilent 2100 Bioanalyzer and the Experion Automated Electrophoresis System. In this study, we evaluated if the CE is able to distinguish the three uridine diphosphate glucuronosyltransferase 1A1 TATA-box genotypes.
KW - Capillary electrophoresis
KW - Lab on a chip
KW - Capillary electrophoresis
KW - Lab on a chip
UR - http://hdl.handle.net/10807/64028
U2 - 10.1002/jssc.201400235
DO - 10.1002/jssc.201400235
M3 - Article
SN - 1615-9306
VL - 37
SP - 1521
EP - 1523
JO - Journal of Separation Science
JF - Journal of Separation Science
ER -