The interaction of Fas with FasL has been demonstrated to be implicated in the pathogenesis of several autoimmune and liver diseases. Recently, attention has been focused on the hypothesis that thyrocytes and Î² cells undergo massive Fas/FasL-mediated apoptosis during autoimmune response. Similarly, hepatocyte cell death occurring following copper accumulation points towards the same mechanism.
|Numero di pagine||5|
|Rivista||Archivum Immunologiae et Therapiae Experimentalis|
|Stato di pubblicazione||Pubblicato - 1999|
- Autoimmune diseases
- Hashimoto's thyroiditis
- Insulin-dependent diabetes mellitus
- Wilson's disease