Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

Gustavo Savino; Remo Battendieri; Andrea Siniscalco; Erika Mandara'; Antonino Mule'; Gianluigi Petrone; Salvatore Traina; Monica Riso

doi:10.1007/s00296-014-3054-7

Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

Gustavo Savino, Remo Battendieri, Andrea Siniscalco, Erika Mandara', Antonino Mule', Gianluigi Petrone, Salvatore Traina, Monica Riso

Risultato della ricerca: Contributo in rivista › Articolo in rivista

12 Citazioni (Scopus)

Abstract

We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.

Lingua originale	English
pagine (da-a)	183-188
Numero di pagine	6
Rivista	Rheumatology International
Volume	35
DOI	https://doi.org/10.1007/s00296-014-3054-7
Stato di pubblicazione	Pubblicato - 2015

Keywords

idiopathic orbital inflammatory syndrome:

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abstract = "We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.",

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T1 - Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

AU - Savino, Gustavo

AU - Battendieri, Remo

AU - Siniscalco, Andrea

AU - Mandara', Erika

AU - Mule', Antonino

AU - Petrone, Gianluigi

AU - Traina, Salvatore

AU - Riso, Monica

PY - 2015

Y1 - 2015

N2 - We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.

AB - We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.

KW - idiopathic orbital inflammatory syndrome:

UR - http://hdl.handle.net/10807/70295

U2 - 10.1007/s00296-014-3054-7

DO - 10.1007/s00296-014-3054-7

M3 - Article

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VL - 35

SP - 183

EP - 188

JO - Rheumatology International

JF - Rheumatology International

ER -

Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

Abstract

Keywords

OSS delle Nazioni Unite

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