TY - JOUR
T1 - Intractable coronary fibromuscular dysplasia leading to end-stage heart failure and fatal heart transplantation
AU - Cattaneo, Magdalena Maria
AU - Moccetti, Marco
AU - Cattaneo, Mattia
AU - Sürder, Daniel
AU - Suter, Thomas
AU - Martinelli, Michele
AU - Roost, Eva
AU - Schmidli, Jürg
AU - Banz, Yara
AU - Schneiders, Carmen
AU - Pedrazzini, Giovanni
AU - Corti, Roberto
AU - Räber, Lorenz
AU - Crea, Filippo
AU - Mohacsi, Paul
AU - Gallino, Augusto
PY - 2020
Y1 - 2020
N2 - Coronary fibromuscular dysplasia is uncommon, and even rarer its unstable and recurrent course. We present the unique case of a 52-year-old woman who underwent in total 12 coronary angiographies and three percutaneous coronary intervention within 24 months because of repetitive acute coronary syndromes due to refractory spasm, dissection, restenosis all leading to end-stage heart failure, and heart transplantation. The patient died 12 days after the heart transplantation complicated by intraoperative acute thrombotic occlusion of left anterior descending artery of the graft despite normal pretransplant coronary angiography. Autopsy of the recipient heart confirmed coronary fibromuscular dysplasia with massive intimal hyperplasia and restenosis.
AB - Coronary fibromuscular dysplasia is uncommon, and even rarer its unstable and recurrent course. We present the unique case of a 52-year-old woman who underwent in total 12 coronary angiographies and three percutaneous coronary intervention within 24 months because of repetitive acute coronary syndromes due to refractory spasm, dissection, restenosis all leading to end-stage heart failure, and heart transplantation. The patient died 12 days after the heart transplantation complicated by intraoperative acute thrombotic occlusion of left anterior descending artery of the graft despite normal pretransplant coronary angiography. Autopsy of the recipient heart confirmed coronary fibromuscular dysplasia with massive intimal hyperplasia and restenosis.
KW - Coronary artery dissection
KW - Coronary fibromuscular dysplasia
KW - Orthotopic heart transplantation
KW - Refractory coronary artery spasm
KW - Coronary artery dissection
KW - Coronary fibromuscular dysplasia
KW - Orthotopic heart transplantation
KW - Refractory coronary artery spasm
UR - http://hdl.handle.net/10807/166991
U2 - 10.1002/ehf2.12626
DO - 10.1002/ehf2.12626
M3 - Article
SN - 2055-5822
VL - 7
SP - 714
EP - 720
JO - ESC heart failure
JF - ESC heart failure
ER -