Intracranial dural based marginal zone MALT-type B-cell lymphoma: a case - Based update and literature review

Giuseppe La Rocca, Anna Maria Auricchio, Edoardo Mazzucchi, T Ius, Giuseppe Maria Della Pepa, R Altieri, Fabrizio Pignotti, Marco Gessi, Vincenzo De Santis, C Zoia, Giovanni Sabatino

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Objectives: Dural based Marginal Zone MALT-type B-Cell Lymphoma (MZBCL) is an intracranial tumor that can mimicking meningioma both from a clinical and a radiological point of view. A standard treatment protocol is still lacking. Aim of the present work is to provide an update of the present literature regarding this rare neoplasia Patients and methods: We report the case of a patient with a dural-based lesion mimicking a meningioma of the tentorium. After surgical treatment, the diagnosis was of MZBCL. A literature review is performed to highlight the typical characteristics of this rare intracranial lesion and to define the best therapeutic approach. Results: Literature review included 38 articles describing 126 cases of intracranial dural-based MZBCL. No clinical trial has been found. Clinical and histopathological features are properly collected to provide a guide for future cases. Different treatment options have been attempted. Combination of surgery with adjuvant radiation therapy is the most used option. Conclusions: MZBCL should be considered in differential diagnosis for dural-based intracranial lesion. Surgery followed by radiation therapy is the most reported treatment. As a consequence of the rarity of this disease, of its indolent progression and of the lack of adequate follow-up, it is not possible to define it is the best treatment option.
Lingua originaleEnglish
pagine (da-a)1480-1486
Numero di pagine7
RivistaBritish Journal of Neurosurgery
Volume37
DOI
Stato di pubblicazionePubblicato - 2023

Keywords

  • Dural-based lesion
  • radiation therapy
  • differential diagnosis
  • cerebral lymphoma

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