Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention

Luigi Marzio Biasucci, Francesco Burzotta, Carlo Trani, Giovanna Liuzzo, Filippo Crea, Italo Porto, Giovanni Luigi De Maria, Antonio Maria Leone, Giampaolo Niccoli, Alessandra Tritarelli, Rocco Vergallo

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Microparticles (MP) are cell-derived fragments known to be increased in the blood of patients with acute coronary syndromes. We aimed to assess, in ST elevation myocardial infarction (STEMI), the systemic and local (in the culprit coronary artery) levels of platelet-derived MP (PMP, CD42+CD31+) and endothelial-derived MP (EMP, CD42-CD31+) and their relation to indexes of microvascular obstruction (MVO).
Lingua originaleEnglish
pagine (da-a)2928-2938
Numero di pagine11
RivistaEuropean Heart Journal
Volume33
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Analysis of Variance
  • Blood Platelets
  • Cell-Derived Microparticles
  • Coronary Occlusion
  • Coronary Thrombosis
  • Endothelium, Vascular
  • Female
  • Humans
  • Male
  • Microcirculation
  • Microvessels
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction
  • Myocardial Reperfusion
  • Percutaneous Coronary Intervention
  • Prospective Studies

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