@article{f60a856b89b54dab8c0e58d6019bdc38,
title = "Intracellular concentration map of magnesium in whole cells by combined use of x-ray fluorescence microscopy and atomic force microscopy",
abstract = "We report a novel experimental approach to derive quantitative concentration map of light elements in whole cells by combining two complementary nano-probe methods: X-ray fluorescence microscopy (XRFM) and atomic force microscopy (AFM). The concentration is derived by normalizing point-by-point the elemental (here Mg) spatial distribution obtained by XRFM, by the thickness measured using AFM. The considerable difference between the elemental distribution and the concentration maps indicates that this procedure is essential to obtain reliable information on the role and function of elements in whole cells",
keywords = "atomic force microscopy, cell element concentration, magnesium, synchrotron radiation, x-ray fluorescence microscopy, atomic force microscopy, cell element concentration, magnesium, synchrotron radiation, x-ray fluorescence microscopy",
author = "S Lagomarsino and S Iotti and G Farruggia and A Cedola and Valentina Trapani and M Fratini and I Bukreeva and A Notargiacomo and L Mastrototaro and C Marraccini and A Sorrentino and I Mcnulty and S Vogt and D Legnini and S Kim and A Gianoncelli and Maier, {J. A. M} and {Wolf Minotti}, Federica",
year = "2011",
language = "English",
pages = "834--840",
journal = "Spectrochimica Acta, Part B: Atomic Spectroscopy",
issn = "0584-8547",
publisher = "Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010",
}