Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

Marta Di Grezia; Pietro Fransvea; Francesco Santullo; Flavio Tirelli; Valeria Fico; Paolo Mirco; Valerio Cozza; Antonio La Greca; Gabriele Sganga

doi:10.1016/j.mehy.2020.109954

Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

Marta Di Grezia
, Pietro Fransvea
, Francesco Santullo
, Flavio Tirelli
, Valeria Fico
, Paolo Mirco
, Valerio Cozza
, Antonio La Greca
, Gabriele Sganga

Risultato della ricerca: Contributo in rivista › Articolo

1 Citazioni (Scopus)

Abstract

COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.

Lingua originale	Inglese
pagine (da-a)	109954-N/A
Rivista	Medical Hypotheses
Volume	144
DOI	https://doi.org/10.1016/j.mehy.2020.109954
Stato di pubblicazione	Pubblicato - 2020

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10.1016/j.mehy.2020.109954

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Di Grezia, M., Fransvea, P., Santullo, F., Tirelli, F., Fico, V., Mirco, P., Cozza, V., La Greca, A., & Sganga, G. (2020). Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function. Medical Hypotheses, 144, 109954-N/A. https://doi.org/10.1016/j.mehy.2020.109954

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title = "Intra-abdominal hypertension as a trigger of {\textquotedblleft}gut failure{\textquotedblright} in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function",

abstract = "COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.",

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author = "\{Di Grezia\}, Marta and Pietro Fransvea and Francesco Santullo and Flavio Tirelli and Valeria Fico and Paolo Mirco and Valerio Cozza and \{La Greca\}, Antonio and Gabriele Sganga",

year = "2020",

doi = "10.1016/j.mehy.2020.109954",

language = "English",

volume = "144",

pages = "109954--N/A",

journal = "Medical Hypotheses",

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Di Grezia, M, Fransvea, P, Santullo, F, Tirelli, F, Fico, V, Mirco, P, Cozza, V, La Greca, A & Sganga, G 2020, 'Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function', Medical Hypotheses, vol. 144, pagg. 109954-N/A. https://doi.org/10.1016/j.mehy.2020.109954

Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function. / Di Grezia, Marta; Fransvea, Pietro; Santullo, Francesco et al.
In: Medical Hypotheses, Vol. 144, 2020, pag. 109954-N/A.

Risultato della ricerca: Contributo in rivista › Articolo

TY - JOUR

T1 - Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

AU - Di Grezia, Marta

AU - Fransvea, Pietro

AU - Santullo, Francesco

AU - Tirelli, Flavio

AU - Fico, Valeria

AU - Mirco, Paolo

AU - Cozza, Valerio

AU - La Greca, Antonio

AU - Sganga, Gabriele

PY - 2020

Y1 - 2020

N2 - COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.

AB - COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.

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UR - http://hdl.handle.net/10807/159060

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DO - 10.1016/j.mehy.2020.109954

M3 - Article

SN - 0306-9877

VL - 144

SP - 109954-N/A

JO - Medical Hypotheses

JF - Medical Hypotheses

ER -

Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

Abstract

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